Simone Weil

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We report the MR imaging findings in two children with glutaric aciduria type I (GA I). It is important to consider this disorder in the differential diagnosis in a child presenting with an unclear hydrocephalus or atrophy. The imaging findings consist of basal ganglia changes, frontotemporal atrophy, and retarded myelination. A definite diagnosis with an(More)
Meningeal sarcomas are very rare, highly aggressive tumours affecting children more frequently than adults. The clinical course and MRI of meningeal sarcomas in two cases are discussed with special regard to possible misinterpretation. In one case MRI demonstrated a circumscribed mass in contact with the meninges, with central areas of haemorrhage. In the(More)
1. Cortisol concentrations were measured in sexually mature female camels (N = 18), two newborn camels and one adult male. 2. The study revealed a significant difference in the amounts of cortisol in pluriparous mated camels (N = 7) during the breeding season before (8.0 +/- 1.3 ng/ml) and immediately after mating, 45.0 +/- 11.9 ng/ml (P less than 0.01). 3.(More)
A 34-year-old man presented with progressive myelopathy 4 months after cadaveric renal transplant for endstage renal disease. Radiographic evaluation gave findings consistent with epidural lipomatosis and compression of the thoracic thecal sac. Decompressive laminectomy resulted in dramatic improvement of his neurologic deficit. This case is unusual in the(More)
OBJECTIVE The objective of this investigation was to identify genes that confer susceptibility to polycystic ovary syndrome. STUDY DESIGN Nineteen subjects with polycystic ovary syndrome, hirsutism, and elevated plasma androgen levels and 46 fertile, female control subjects were studied. Alleles at the human leukocyte antigen DQA1 locus were identified(More)
5056 Background: Farletuzumab (FAR) is a humanized monoclonal antibody that binds to the folate receptor alpha, a potentially attractive target since it is over-expressed in EOC but is largely absent in normal epithelium. A Phase I dose escalation of FAR in platinum-resistant EOC showed no dose-limiting toxicities. A Phase II study of FAR with carboplatin(More)