Simone Schmid

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Protein kinase D (PKD) has been identified as a crucial regulator of secretory transport at the trans-Golgi network (TGN). Recruitment and activation of PKD at the TGN is mediated by the lipid diacylglycerol, a pool of which is generated by sphingomyelin synthase from ceramide and phosphatidylcholine. The nonvesicular transfer of ceramide from the(More)
1 Stand der Forschung Das Thema Wandlungsfähigkeit ist ein relativ junges Forschungsgebiet, das zu-nächst über den Betrachtungsbereich der Fabrikplanung in den Fokus von Indust-rie und Forschung gerückt ist. Wandlungsfähigkeit wird in der Fabrikplanung als neues Ziel angesehen. Unter verschiedenen Aspekten wurden Gestaltungsrichtlinien für modulare und(More)
Epithelial cell-cell contacts are mediated by E-cadherin interactions, which are regulated by the balanced local activity of Rho GTPases. Despite the known function of Rho at adherens junctions (AJs), little is known about the spatial control of Rho activity at these sites. Here we provide evidence that in breast epithelial cells the Deleted in Liver Cancer(More)
AbstrAct The Knowledge Modeling and Description Language (KMDL ®) allows analysts to identify process patterns, which leads to improvements in knowledge-intensive processes. After modeling the business processes, knowledge and process potentials in daily business processes can be unleashed. The following contribution presents a specification of KMDL ® for(More)
The growth factor heregulin (HRG) potently stimulates epithelial cell survival and proliferation through the binding of its cognate receptor ErbB3 (also known as HER3). ErbB3-dependent signal transmission relies on the dimerization partner ErbB2, a receptor tyrosine kinase that is frequently overexpressed and/or amplified in breast cancer cells. Substantial(More)
  • Univ, Norbert Gronau, J Bogen, N Gronau, S Schmid, Zitierhinweis Bogen +5 others
  • 2005
Modeling some instances of software development processes with a specialized modeling technique can improve the knowledge management in software engineering in general and in small and medium companies as well. The modeling with the Knowledge Modeling and Description Language KMDL ® allows to identify process patterns from which improvements for the(More)
In two experiments, we transferred perceptual load theory to the dynamic field of team sports and tested the predictions derived from the theory using a novel task and stimuli. We tested a group of college students (N = 33) and a group of expert team sport players (N = 32) on a general perceptual load task and a complex, soccer-specific perceptual load task(More)