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Thermodynamically consistent orthotropic activation model capturing ventricular systolic wall thickening in cardiac electromechanics
The complex phenomena underlying mechanical contraction of cardiac cells and their influence in the dynamics of ventricular contraction are extremely important in understanding the overall functionExpand
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Orthotropic active strain models for the numerical simulation of cardiac biomechanics.
A model for the active deformation of cardiac tissue considering orthotropic constitutive laws is introduced and studied. In particular, the passive mechanical properties of the myocardium areExpand
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Integrated Heart—Coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like otherExpand
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Anisotropic Modeling of Cardiac Mechanical Activation
Keywords: Cardiac electromechanics ; Active strain formulation ; Configurational forces ; Monodomain model ; Finite element method These Ecole polytechnique federale de Lausanne EPFL, n° 6120Expand
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Activation Models for the Numerical Simulation of Cardiac Electromechanical Interactions
This contribution addresses the mathematical modeling and numerical approximation of the excitation-contraction coupling mechanisms in the heart. The main physiological issues are preliminarilyExpand
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Mathematical modelling of active contraction in isolated cardiomyocytes.
We investigate the interaction of intracellular calcium spatio-temporal variations with the self-sustained contractions in cardiac myocytes. A consistent mathematical model is presented considering aExpand
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A Three-dimensional Continuum Model of Active Contraction in Single Cardiomyocytes
We investigate the interaction of intracellular calcium spatio-temporal variations with the self-sustained contractions in cardiac myocytes. A 3D continuum mathematical model is presented based on aExpand
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Active strain and activation models in cardiac electromechanics
We present a model for mechanical activation of the cardiac tissue depending on the evolution of the transmembrane electrical potential and certain gating/ionic variables that are available in mostExpand
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Muscle Thickness and Curvature Influence Atrial Conduction Velocities
Electroanatomical mapping is currently used to provide clinicians with information about the electrophysiological state of the heart and to guide interventions like ablation. These maps can be usedExpand
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On some numerical aspects of an active strain model in cardiac mechanics
We are interested in the development, implementation and testing of an orthotropic model for cardiac contraction based on an active strain decomposition. Our model addresses the coupling of aExpand