Simona Gardini

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Personality dimensions such as novelty seeking (NS), harm avoidance (HA), reward dependence (RD) and persistence (PER) are said to be heritable, stable across time and dependent on genetic and neurobiological factors. Recently a better understanding of the relationship between personality traits and brain structures/systems has become possible due to(More)
Previous studies of hormonal and neurophysiological changes in response to psychological stress in humans have produced contrasting findings due to differing experimental procedures and consistent individual variability. Habituation effects, which influence physiological coping in response to exposure to repeated stress, need to be investigated more(More)
Alcohol use, "alcohol abuse," and illicit drug use were investigated in a representative sample of 1076 urban, northern Italian high school students aged 14 to 19 years in 2001. In addition to questions on substance use, the participants were asked about school achievements and perceived substance use among friends. All the students were submitted to(More)
BACKGROUND The Clock Drawing Test (CDT) is a valid screening tool for the evaluation of cognitive decline. This study aimed to compute standardized norms for the Freedman version of the CDT in a population of 248 healthy Italian individuals aged from 20 to 89 years. METHOD The effects of age, education, and gender on performance were assessed. Three(More)
Twelve (+/-) 3,4-methylenedioxymethamphetamine (MDMA) users, who did not show other drug dependencies or prolonged alcohol abuse (group A), and 12 control subjects (group B) were included in the study. Prolactin (PRL) and growth hormone (GH) responses to the dopaminergic agonist bromocriptine (BROM) and psychometric measures were evaluated 3 weeks after(More)
The aim of this functional magnetic resonance imaging (fMRI) study was to investigate the neuroanatomical substrates associated with the process of mental generation of specific (i.e., exemplar) and episodic autobiographical (i.e., an image of a unique life episode connected with an object) images. The fMRI paradigm in this experiment included a non-image(More)
Four experiments examined attentional capture by colour as assessed by two different investigative methods. Subjects performed a visual search task for a vertical-target line embedded among tilted-distractor lines, presented inside 4, 8, or 12 coloured discs. Interestingly, when the colour singleton was task irrelevant, and data were analysed by means of(More)
Semantic memory decline has been found in mild cognitive impairment (MCI). In this study performance on a range of semantic tasks and structural brain patterns were examined in a group of MCI patients. Fourteen MCI and sixteen healthy elderly controls underwent semantic memory assessment and MRI brain scanning. The cognitive battery included visual naming(More)
OBJECTIVE The present study investigated the attentional bias induced by drug-related stimuli in active abusers; abstinent abusers on opioid substitution therapy; and abstinent drug-dependent patients in recovery on a community-based non-pharmacological therapy programme. Drug-dependent groups included both cocaine and heroin abusers. METHODS Classical(More)
Mental image generation is a complex process mediated by dynamically interrelated components, e.g. image generation and image enrichment of details. This study investigated the cognitive and neural correlates of sequential image generation. An event-related fMRI experiment was carried out in which general and specific images had to be generated sequentially(More)