Simona C Eremia

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To date, there is no known prenatal treatment for intrauterine growth restriction (IUGR). IGF-I is an important regulator of fetal growth and circulating IGF-I concentrations are reduced in IUGR fetuses. We investigated whether any of three different methods of fetal IGF-I administration would reverse IUGR in sheep. Animals were randomized into five groups:(More)
OBJECTIVE This study was undertaken to investigate whether maternal growth hormone supplementation in pregnant sheep could reverse intrauterine growth restriction (IUGR) induced by placental embolization. STUDY DESIGN Animals were randomized into control, intrauterine growth restriction + saline or intrauterine growth restriction + growth hormone (twice(More)
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