Simona Apostol

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The type 1 isoform of the ryanodine receptor (RYR1) is the Ca(2+) release channel of the sarcoplasmic reticulum (SR) that is activated during skeletal muscle excitation-contraction (EC) coupling. Mutations in the RYR1 gene cause several rare inherited skeletal muscle disorders, including malignant hyperthermia and central core disease (CCD). The human(More)
Strenuous activitiy of skeletal muscle leads to temporary osmotic dysbalance and isolated skeletal muscle fibers exposed to osmotic stress respond with characteristic micro-domain calcium signals. It has been suggested that osmotic stress targets transverse tubular (TT) dihydropyridine receptors (DHPRs) which normally serve as voltage-dependent activators(More)
The effect of irradiance during low temperature hardening was studied in a winter wheat variety. Ten-day-old winter wheat plants were cold-hardened at 5 degrees C for 11 days under light (250 micromol m(-2) S(-1)) or dark (20 micromol m(-2) s(-1)) conditions. The effectiveness of hardening was significantly lower in the dark, in spite of a slight decrease(More)
The effect of cumulative over-saturating pulses (OSP) of white light (1 s, >10 000 μmol photons m−2 s−1), applied every 20 min on pea leaves, was investigated during a complete diurnal cycle of 24 h. In dark-adapted leaves, this treatment leads to a progressive decline of the optimum Photosystem II (PS II) quantum yield. Continuous low background light(More)
The interaction between light and temperature during the development of freezing tolerance was studied in winter wheat (Triticum aestivum L. var. Mv Emese). Ten-day-old plants were cold hardened at 5 degrees C for 12 days under normal (250 micromol m(-2)s(-1)) or low light (20 micromol m(-2)s(-1)) conditions. Some of the plants were kept at 20/18 degrees C(More)
We compared the sensitivity to cold stress, in terms of photosynthetic capacity and changes in chlorophyll fluorescence of photosystem 2 (PS2), of an evergreen and a deciduous oak species, which co-occur in the southeastern United States. We predicted that the evergreen species, Quercus virginiana, which must endure winter, is likely to have an inherently(More)
The reactions of the flavin semiquinone generated by laser-induced stepwise two-photon excitation of reduced flavin have been studied previously (El Hanine-Lmoumene C & Lindqvist L. (1997) Photochem Photobiol 66, 591-595) using time-resolved spectroscopy. In the present work, we have used the same experimental procedure to study the flavin semiquinone in(More)
A simple method of characterising epithelial and endothelial corneal cells using laser light is presented. A continuous wave helium-neon laser emitting at a wavelength of 632.8 nm and a continuous wave argon laser emitting at 488 and 514.5 nm were used. The cell images obtained were used to calculate the dimensions of the endothelial corneal cells, a(More)
The RYR1 functions as the Ca release channel in the skeletal muscle SR. The functional RYR1 SR Ca release channel is a 2.3-megadalton homomeric assembly of four 565-kD RYR1 subunits. Each RYR1 subunit is composed of a large N-terminal cytosolic “foot” region and six to eight transmembrane sequences located within the C-terminal portion of the protein (Du(More)
The present study represents"The Fislab package of programs meant to develop the fuzzy regulators in the Scilab environment"in which we present some general issues, usage requirements and the working mode of the Fislab environment. In the second part of the article some features of the Scilab functions from the Fislab package are described.