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OBJECTIVE To evaluate and determine the most effective immunosuppressive therapy for the induction treatment of proliferative lupus nephritis (PLN) based on renal remission. METHODS A systematicContinue Reading
  • Simon Yu Tian, Brian M Feldman, Joseph Beyene, Patrick E. Brown, Elizabeth Uleryk, Earl D Silverman
  • Medicine
  • The Journal of rheumatology
  • 2014 (First Published: 1 October 2014)
  • OBJECTIVE To determine the most effective immunosuppressive therapy for the longterm management of proliferative lupus nephritis (PLN) based on the outcome of renal failure. METHODS A systematicContinue Reading
  • Simon Yu Tian, Earl D Silverman, Eleanor M Pullenayegum, Patrick E. Brown, Joseph Beyene, Brian M Feldman
  • Medicine
  • Arthritis care & research
  • 2017 (First Published: 1 December 2017)
  • OBJECTIVE Although juvenile-onset proliferative lupus nephritis (PLN) leads to significant morbidity and mortality, there is no clinical trials-based evidence to support the treatment effectivenessContinue Reading
  • Simon Yu Tian, Jun-feng Wang, Yarema B. Bezchlibnyk, Lionel Trevor Young
  • Biology
  • Neuroscience Letters
  • 2007 (First Published: 10 January 2007)
  • Impairment of neuroplasticity is considered to play a role in the pathogenesis of psychiatric disorders. To further characterize the impairment of neuroplasticity in psychiatric disorders, expressionContinue Reading
  • Margaret Rosenfeld, Steve Cunningham, +9 authors Jane C Davies
  • Medicine
  • Journal of cystic fibrosis : official journal of…
  • 2019 (First Published: 1 April 2019)
  • BACKGROUND KIWI (NCT01705145) was a 24-week, single-arm, pharmacokinetics, safety, and efficacy study of ivacaftor in children aged 2 to 5 years with cystic fibrosis (CF) and a CFTR gating mutation.Continue Reading