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  • Maziyar Saberi, N. J. Woods, +5 authors Jerrold M. Olefsky
  • Medicine, Biology
  • Cell metabolism
  • 2009 (First Publication: 1 November 2009)
  • Chronic low-grade inflammation, particularly in adipose tissue, is an important modulator of obesity-induced insulin resistance. The Toll-like receptor 4 (Tlr4) is a key initiator of inflammatoryContinue Reading
  • Andrew Philp, Ai Chen, +9 authors Simon Schenk
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2011 (First Publication: 2 September 2011)
  • The protein deacetylase, sirtuin 1 (SIRT1), is a proposed master regulator of exercise-induced mitochondrial biogenesis in skeletal muscle, primarily via its ability to deacetylate and activateContinue Reading
  • Simon Schenk, Matthew P. Harber, Cara R Shrivastava, Charles F. Burant, Jeffrey F Horowitz
  • Medicine, Chemistry
  • The Journal of physiology
  • 2009 (First Publication: 15 October 2009)
  • Obesity is characterized by excessive rates of plasma fatty acid mobilization and uptake, which play a key role in mediating insulin resistance. While weight loss via diet-only or a diet + exerciseContinue Reading
  • Simon Schenk, Jeffrey F Horowitz
  • Biology, Medicine
  • American journal of physiology. Endocrinology and…
  • 2006 (First Publication: 1 August 2006)
  • Although the increase in fatty acid oxidation after endurance exercise training has been linked with improvements in insulin sensitivity and overall metabolic health, the mechanisms responsible forContinue Reading
  • Sean A. Newsom, Simon Schenk, +4 authors Jeffrey F Horowitz
  • Medicine
  • Journal of applied physiology
  • 2010 (First Publication: 1 March 2010)
  • The content of meals consumed after exercise can impact metabolic responses for hours and even days after the exercise session. The purpose of this study was to compare the effect of low dietaryContinue Reading