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  • Tracey R. O’Donovan, Simon Rajendran, Seamus O’Reilly, Gerald C O'sullivan, Sharon L. McKenna, Ilya V Ulasov
  • Medicine, Biology
  • PloS one
  • 2015 (First Publication: 6 August 2015)
  • Many epithelial cancers, particularly gastrointestinal tract cancers, remain poor prognosis diseases, due to resistance to cytotoxic therapy and local or metastatic recurrence. We have previouslyContinue Reading
  • Sarfraz Ahmad, Garrett Casey, +4 authors Gerald C O'sullivan
  • Medicine, Biology
  • The Journal of urology
  • 2011 (First Publication: 1 August 2011)
  • PURPOSE The induction of systemic immune responses against antigenic targets that are over expressed by cancer cells represents a powerful therapeutic strategy to target metastatic cancer. WeContinue Reading
  • Simon Rajendran, Philip Hodgnett, Deirdre O'Hanlon, Andrew Curtain, Micheal G. Murphy
  • Medicine
  • Gynecologic oncology
  • 2009 (First Publication: 1 September 2009)
  • BACKGROUND Iatrogenic trauma is the leading cause of ureteric injury with an incidence in abdominal and pelvic surgery varying between 0.4 and 2.5%. CASE We report a case of ureteric obstructionContinue Reading
  • Simon Rajendran, Deirdre Elizabeth O'Hanlon, David Morrissey, Tracey R. O’Donovan, Gerald C O'sullivan, Mark Tangney
  • Biology, Medicine
  • Experimental biology and medicine
  • 2011 (First Publication: 1 April 2011)
  • Preclinical results with various gene therapy strategies indicate significant potential for new cancer treatments. However, many therapeutics fail at clinical trial, often due to differences inContinue Reading