Simon P. Kanaan

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One goal of contemporary proteome research is the elucidation of cellular protein interactions. Based on currently available protein-protein interaction and domain data, we introduce a novel method, Maximum Specificity Set Cover (MSSC), for the prediction of protein-protein interactions. In our approach, we map the relationship between interactions of(More)
The ever accumulating wealth of knowledge about protein interactions and the domain architecture of involved proteins in different organisms offers ways to understand the intricate interplay between interactome and proteome. Ultimately, the combination of these sources of information will allow the prediction of interactions among proteins where only domain(More)
— A goal of contemporary proteome research is the elucidation of the protein-protein interactions in the cell. Based on currently available protein-protein interaction and domain data of S. cerevisiae, we introduce a novel method, Maximum Specificity Set Cover (MSSC), to predict protein-protein interactions. This algorithm features two stages: First, we(More)
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