Simon McDonald

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Heart rate is dependent on a cycle of depolarization and repolarization of the atria and ventricles that is regulated by intrinsic and extrinsic factors. Inhomogeneity in ventricular repolarization, measured as QT interval dispersion (QTd) is likely to lead to arrhythmia. The role of the autonomic nervous system in the development of this inhomogeneity is(More)
Improving risk assessment to provide evidence for preventative intervention has recently become more of a focus in cardiovascular medicine with atherosclerosis as an early manifestation of cardiovascular disease. The total cholesterol to high-density lipoprotein (TC/HDL) ratio is often used an atherogenic index. High levels of the TC/HDL ratio also affect(More)
To determine whether rheumatoid arthritis disease activity correlates with changing weather conditions. A longitudinal analysis of 133 patients attending the Department of Rheumatology, Musgrave Park Hospital, Belfast was performed. Participants had a diagnosis of rheumatoid arthritis and were receiving subcutaneous anti-TNF therapy (Adalimumab or(More)
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