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The data brought together in this report have been gathered from a wide territory and for a period extending over several years. The antimeningitis serum was first employed in 1906 and the latest figures relating to its use included in this report were furnished in 1912. There is no longer doubt that the serum has come to be applied under conditions fairly(More)
It is our belief that the analyses of histories of cases of epidemic meningitis which have been presented in this article furnish convincing proof that the antimeningitis serum when used by the subdural method of injection, in suitable doses and at proper intervals, is capable of reducing the period of illness; of preventing, in large measure, the chronic(More)
Several attempts have been made to demonstrate under the microscope and to develop in artificial cultures the microSrganism causing epidemic poliomyelitis, but hitherto unsuccessfully. Giers-vold 1 cultivated certain micrococci from the cerebrospinal fluid, and Fox 2 a bacillus from the circulating blood of poliomyelitic patients, but both have now been(More)
The experimental study of poliomyelitis has yielded a large number of important facts relating to the spontaneous disease in man. The nature of the virus has been discovered, many of its properties have been ascertained, some of its immunity effects have been established, the clinical and pathological peculiarities of the disease have been elucidated, and a(More)
At the beginning of my study of Diplococcus intracellularis I had the plan of using monkeys to reproduce the symptoms and lesions of cerebro-spinal meningitis in man. My study of the intra-peritoneal injections of guinea-pigs encouraged me to believe that the injection of suitable cultures of the intraceUularis into the spinal canal of monkeys would lead to(More)
The study of the effects of the living pathogenic organisms upon the animal body has been succeeded by an era in which especial atten-t-ion has been directed to the influence of their soluble products. The researches of Oertel* upon human diphtheria, of Babes t and of Welch and Flexner$ upon the experimental form of the disease, the latter including the(More)