Simon D. Carr

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BACKGROUND To determine total upper limb function following selective neck dissection over a mean follow-up of 1.6 years. METHODS A retrospective questionnaire study in a tertiary head and neck surgical unit. One hundred forty-eight patients who underwent selective neck dissection for head and neck cancer from January 2000 to December 2005 were invited to(More)
OBJECTIVE To identify factors that significantly influence myringoplasty success. METHODS A retrospective study was performed of all adults and children who underwent myringoplasty from January 2005 to January 2010 in a teaching hospital. Outcome measures were tympanic membrane perforation closure and air-bone gap closure to within 20 dB HL. The factors(More)
Alfentanil is becoming an alternative to diamorphine when parental opioids are required, especially in the presence of renal insufficiency. Its pharmacokinetic properties suggest that tolerance may be rapidly induced, whilst concomitant administration of drugs that interfere with the cytochrome P450 system may alter its metabolism. This retrospective audit(More)
BACKGROUND The management of chronic rhinosinusitis is based on a trial of "maximal medical therapy" before surgery is considered. Ear-Nose-Throat (ENT) UK consultant members were surveyed to determine the role and variability of UK-wide practices. METHODS A survey was posted to all ENT UK consultant members (n = 603). This assessed the frequency of(More)
We and others have previously described signatures of tolerance in kidney transplantation showing the differential expression of B cell-related genes and the relative expansions of B cell subsets. However, in all of these studies, the index group-namely, the tolerant recipients-were not receiving immunosuppression (IS) treatment, unlike the rest of the(More)
OBJECTIVES A relationship between Meniere's disease and migraine has been postulated previously. This study investigates this relationship further and determines the most influential factors for developing Meniere's disease. DESIGN Epidemiological study. SETTING Two tertiary referral Neuro-Otological centres in Sheffield and Sydney. PARTICIPANTS Adult(More)
OBJECTIVES To determine the accuracy of fine needle aspiration cytology conducted within a standard ENT out-patients service (rather than a one-stop neck lump clinic), and also to assess the value of ultrasound guidance during fine needle aspiration cytology. DESIGN Retrospective study of all patients undergoing fine needle aspiration cytology of a neck(More)
To determine whether an elderly population with hearing impairment can be adequately rehabilitated with a bone-conduction hearing aid and whether the putative relationship between the elderly and an increased complication rate is justified. The study design was a retrospective case note review with a postal and telephone questionnaire, which was carried out(More)
OBJECTIVE The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment. STUDY DESIGN Feasibility study. SETTING Tertiary referral center. SUBJECTS AND METHODS Thirty-five patients with HNSCC were(More)
OBJECTIVE To assess outcomes with a new transcutaneous bone conduction hearing aid. PATIENTS Patients that underwent implantation with the transcutaneous bone conduction device between November 2013 and May 2014. INTERVENTION Hearing rehabilitation using the BAHA Attract. MAIN OUTCOME MEASURES Quality of life measures using Glasgow benefit inventory(More)