Simon Bourcier

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Thenar eminence tissue oxygen saturation (StO2) was developed to assess organ perfusion. However, mottling, a strong predictor of mortality in septic shock, develops preferentially around the knee. We aimed to evaluate the prognostic value of StO2 measured around the knee in septic shock patients and compare it to thenar StO2. This was a prospective(More)
In the intensive care unit (ICU), the outcomes of patients with acute mesenteric ischemia (AMI) are poorly documented. This study aimed to determine the risk factors for death in ICU patients with AMI. A retrospective, observational, non-interventional, multicenter study was conducted in 43 ICUs of 38 public institutions in France. From January 2008 to(More)
BACKGROUND & AIMS Skin perfusion alterations are early and strong predictors of death in patients with septic shock. Cirrhosis is associated with systemic vasodilation and increases mortality from septic shock. We aimed at assessing whether the mottling score and tissue oxygen saturation (StO2) could be used as early predictors of death in cirrhotic(More)
BACKGROUND Mottling score has been reported to be a strong predictive factor during septic shock. However, the pathophysiology of mottling remains unclear. METHODS In patients admitted in ICU for septic shock, we measured on the same area the mean skin perfusion by laser Doppler, the mottling score, and variations of both indices between T1 (6 hours after(More)
Terminal extubation (TE) and terminal weaning (TW) are the methods available for withdrawing mechanical ventilation. Perceptions of TE and TW by intensive care unit (ICU) staff may influence bedside practices and the feasibility of studies comparing these methods. From January to June 2013, 5 nurses and 5 physicians in each of 46 (out of 70, 65.7 %) French(More)
PURPOSE OF REVIEW Despite the progress made over the past 20 years in the treatment of septic shock, mortality remains high. Microcirculatory disorders raise considerable interest aiming to improve the understanding of the physiopathology of septic shock and its management. RECENT FINDINGS Numerous experimental and clinical studies have gradually focused(More)
Dear Editor, Post-mortem examination relying on medical autopsy is the standard of reference in clinical medicine. Unfortunately, medical autopsy rate has declined worldwide in the few last decades for many reasons, the most frequent being family refusal. Post-mortem imaging using CT scan (virtopsy) is emerging as an alternative to conventional autopsy.(More)
The relative merits of immediate extubation versus terminal weaning for mechanical ventilation withdrawal are controversial, particularly regarding the experience of patients and relatives. This prospective observational multicentre study (ARREVE) was done in 43 French ICUs to compare terminal weaning and immediate extubation, as chosen by the ICU team.(More)
OBJECTIVE Abdominal aortic aneurysm is an inflammatory disease leading to destructive vascular remodeling and ultimately to lethal aortic rupture. Despite its frequent association with atherosclerosis, compelling studies have shown striking differences and potentially opposite roles of T-cell helper responses in aneurysm as compared with atherosclerosis,(More)
We read with interest the study by Knoop et al who reported deleterious effects of antibiotics on the intestinal microflora. This observation should motivate the development of powerful tools for the diagnosis of infections to limit inappropriate antibiotic prescription. Spontaneous bacterial peritonitis (SBP) in patients with cirrhosis is a frequent(More)