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  • Kurt Zimmermann, Jürgen Grünberg, Michael Honer, Simon Ametamey, Pius August Schubiger, Ilse Novak-Hofer
  • Chemistry, Medicine
  • Nuclear medicine and biology
  • 2003 (First Publication: 1 May 2003)
  • In order to optimize radiocopper labeling of anti-L1-CAM antibody chCE7, five bifunctional copper chelators were synthesized and characterized (CPTA-N-hydoxysuccinimide,Expand
  • Carl-Gunnar Swahn, Christer Halldin, Ilonka Guenther, J. T. Patt, Simon Ametamey
  • Chemistry
  • 1996 (First Publication: 1 July 1996)
  • The full synthesis of the cocaine congener 2β-carbomethoxy-3β-(4-iodophenyl)tropane (β-CIT) and its N-fluoroalkyl analogues, fluoroethyl- and fluoropropyl-nor-β-CIT (β-CIT-FE and β-CIT-FP) startingExpand
  • Jürgen Grünberg, Ilse Novak-Hofer, +6 authors Pius August Schubiger
  • Biology, Medicine
  • Clinical Cancer Research
  • 2005 (First Publication: 15 July 2005)
  • Purpose: The L1 cell adhesion protein is overexpressed in tumors, such as neuroblastomas, renal cell carcinomas, ovarian carcinomas, and endometrial carcinomas, and represents a target for tumorExpand
  • Karin Knogler, Jürgen Grünberg, +7 authors Ilse Novak-Hofer
  • Biology, Medicine
  • Clinical Cancer Research
  • 2007 (First Publication: 15 January 2007)
  • Purpose: We examined the tumor-targeting and therapeutic effects of 67Cu-labeled single amino acid mutant forms of anti-L1 monoclonal antibody chCE7 in nude mice with orthotopically implanted SKOV3ipExpand
  • Peter Blaeuenstein, Nicolle Remy, Alfred Buck, Simon Ametamey, M Häberli, Pius August Schubiger
  • Chemistry, Medicine
  • Nuclear medicine and biology
  • 1998
  • The reversible and highly selective monoamine oxidase B (MAO-B) inhibitor Ro 19-6327, a picolinic acid derivative, was selected for the development of new radiopharmaceuticals, whereby in place of ClExpand
  • Samuel Samnick, N Rémy, Simon Ametamey, Jochen Bader, Wolfgang Brandau, Claudine Kirsch
  • Chemistry, Medicine
  • Life sciences
  • 1998 (First Publication: 1 October 1998)
  • In vitro binding study on bovine brain membranes using [3H]SCH23390, [3H]spiperone, [3H]prazosin and [3H]RP62203 as radioligands (for D1, D2, alpha1 and 5-HT2A receptors respectively) indicate thatExpand