Simcha Srebnik

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Biopolymers adsorb on cell and virus surfaces with great specificity. Recently, theoretical and computational studies have inquired as to whether there are any universal design strategies that nature employs in order to affect such recognition. Specifically, the efficacy of multifunctionality and quenched disorder as essential design strategies has been(More)
This paper presents a study of protein adsorption and denaturation using coarse-grained Monte Carlo simulations with simulated annealing. Intermolecular interactions are modeled using the Miyazawa-Jernigan (MJ) knowledge-based potential for an implicit solvent. Three different hydrophobicity scales are tested for adsorption of fibronectin on a hydrophobic(More)
A new technique for microscopic imaging of electrochemically active surfaces is introduced. The technique combines concepts of probe microscopy and advances in mass spectrometry. The technique is based on a miniature electrochemical flow cell scanner. A liquid feed stream containing a redox component is introduced to the vicinity of the examined location(More)
α-Helices are the most abundant structures found within proteins and play an important role in the determination of the global structure of proteins and their function. Representation of α-helical structures with the common (φ, ψ) dihedrals, as in Ramachandran maps, does not provide informative details regarding the helical structure apart for the abstract(More)
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