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  • Silviu Sbiera, Ellen Leich, +17 authors Matthias Kroiss
  • Biology, Medicine
  • Endocrinology
  • 2015 (First Publication: 25 August 2015)
  • Adrenocortical carcinoma (ACC) is a rare malignancy that harbors a dismal prognosis in advanced stages. Mitotane is approved as an orphan drug for treatment of ACC and counteracts tumor growth andExpand
  • Juliane Lippert, Silke Appenzeller, +14 authors Cristina L Ronchi
  • Medicine
  • The Journal of clinical endocrinology and…
  • 2018 (First Publication: 1 December 2018)
  • Context Adrenocortical carcinoma (ACC) has a heterogeneous prognosis, and current medical therapies have limited efficacy in its advanced stages. Genome-wide multiomics studies identified molecularExpand
  • Cristina L Ronchi, Matthias Kroiss, Silviu Sbiera, Timo Deutschbein, Martin Fassnacht
  • Medicine
  • European journal of endocrinology
  • 2014 (First Publication: 1 July 2014)
  • Adrenocortical carcinoma (ACC) is not only a rare and heterogeneous disease but also one of the most aggressive endocrine tumors. Despite significant advances in the last decade, its pathogenesis isExpand