Silvio Luis da Silveira Rocha

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The antibothropic fraction (ABF) already isolated from Didelphis marsupialis serum, inhibits the haemorrhagic, oedematogenic, myonecrotic and lethal activities of Bothrops jararaca venom (Bjv). The aim of this work was to verify the capability of ABF to inhibit the hyperalgesic activity of Bjv. Intraplantar injection of Bjv induced hyperalgesia in a time-(More)
Pasteurella multocida causes atrophic rhinitis in swine and fowl cholera in birds, and is a secondary agent in respiratory syndromes. Pathogenesis and virulence factors involved are still poorly understood. The aim of this study was to detect 22 virulence-associated genes by PCR, including capsular serogroups A, B and D genes and to evaluate the(More)
Two experiments investigated the dose and time related effects of morphine sulfate on the running wheel activity of golden Syrian hamsters. Compared with saline controls, a low dose (5 mg/kg) increased locomotor activity, whereas high doses (10, 20 and 40 mg/kg) produced an initial dose-related depression in activity, a gradual dose-related recovery and(More)
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