Silvia Ruggieri

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OBJECTIVE To compare the long-term efficacy and safety of ropinirole with bromocriptine over 3 years in patients with early PD with limited or no previous dopaminergic therapy. METHODS In this prospective, double-blind, parallel-group study, 335 patients were randomized to 0.75 mg ropinirole or 1.25 mg bromocriptine titrated upward at weekly(More)
BACKGROUND The prognosis of patients with locally advanced nonsmall cell lung carcinoma (NSCLC), which is usually unresectable, is very poor, and patient survival rarely reaches 1 year. However, prolonged survival correlated with objective responses has been observed among patients with intrathoracic disease treated with a combination of cytotoxic drugs and(More)
BACKGROUND High levels of indoor NO2 are associated with increased asthma symptoms and decreased expiratory peak flows in children. We investigated the association of exposure to domestic indoor NO2, objectively measured in winter and spring, with respiratory symptoms and lung function in a sample of adolescents from a southern Mediterranean area. METHODS(More)
GH plays an important role in longitudinal bone growth and maturation during childhood and adolescence. However, GH has important metabolic functions other than bone growth, which become more apparent during young adulthood, when growth has been completed. Indeed, GH deficiency (GHD) in adult life is a recognized clinical syndrome which includes symptoms(More)
The reaction of [Rh7(CO)16]3- with BiCl3 under N2 and at room temperature results in the formation of the new heterometallic [Bi@Rh12(CO)27]3- cluster in high yields. Further controlled addition of BiCl3 leads first to the formation of the dimeric [(Bi@Rh12(CO)26)2Bi]5- and the closo-[Bi@Rh14(CO)27Bi2]3- species in low yields, and finally, to the(More)
Teratomas are germ cell tumors. Mediastinum is the second most common extra-gonadal site of these tumors.[1-3] Mediastinal masses in children and adolescents are usually considered malignant. Even benign teratomas have been reported to transform to malignant ones in case of delayed diagnosis or presentation.[3-5] Moreover, large mediastinal teratoma without(More)
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