Silvia Obenauer

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To evaluate the performance of experienced versus inexperienced radiologists in comparison and in consensus with an interactive computer-aided detection (CAD) system for detection of pulmonary nodules. Eighteen consecutive patients (mean age: 62.2 years; range 29–83 years) prospectively underwent routine 16-row multislice computed tomography (MSCT). Four(More)
The goal of this prospective study was to compare a full-field digital mammography system (FFDM) to a conventional screen-film mammography system (SFM) for the detection and characterization of microcalcifications. Fifty-five patients with 57 isolated microcalcification clusters were examined using a FFDM system (Senographe 2000D, GE Medical Systems,(More)
The purpose of this study was to evaluate the performance of a computer-assisted diagnostic (CAD) tool using various reconstruction slice thicknesses (RST). Image data of 20 patients undergoing multislice CT for pulmonary metastasis were reconstructed at 4.0, 2.0 and 0.75 mm RST and assessed by two blinded radiologists (R1 and R2) and CAD. Data were(More)
Recently, deregulated expression of the anti-apoptotic protein Bax inhibitor-1 (BI-1) has been shown in several human cancers. In this report, we show that BI-1 is expressed at various levels in six different human breast cancer cell lines. In order to investigate the function of BI-1 in oestrogen-dependent MCF-7, T-47D and oestrogen-independent MDA-MB-231(More)
PURPOSE Our goal was to compare digital magnification mammograms with images zoomed from the digital contact mammogram in patients with microcalcifications. PATIENTS AND METHODS Fifty-five patients with 57 microcalcification clusters were evaluated with a FFDM system (Senographe 2000D, GE). In addition to a digital contact mammogram, a digital direct(More)
The Breast Imaging Reporting and Data System (BI-RADS) of the American College of Radiology (ACR) is a tool created to reduce variability in the terminology used in mammographic reports. An illustration of mammographic examples from our institution interpreted according to the BI-RADS lexicon of the American College of Radiology (ACR) is presented. A(More)
A case of a large low-grade mixed clear-cell and conventional chondrosarcoma of the larynx is reported involving the paraglottic space, the cricoid and thyroid cartilage and characterized by an unusual long clinical course over 22 years, although multiple recurrences occurred without developing metastases. Computed tomography suggests diagnosis by detecting(More)
AIM To evaluate prospectively the influence of pulmonary nodule characteristics on detection performances of a computer-aided diagnosis (CAD) tool and experienced chest radiologists using multislice CT (MSCT). MATERIALS AND METHODS MSCT scans of 20 consecutive patients were evaluated by a CAD system and two independent chest radiologists for presence of(More)
PURPOSE Determination of average glandular dose with a full-field digital mammography system using a flat-panel X-ray detector based on amorphous silicon technology for a large group of patients. MATERIAL AND METHODS The patient group includes women who were examined in a 4-month period with the digital mammographic system Senographe 2000D. The number of(More)
The objective of this study was to compare screen-film mammography (SFM) to full-field digital mammography (FFDM) regarding image quality as well as detectability and characterization of lesions using equivalent images of the same patient acquired with both systems. Two mammography units were used, one with a screen-film system (Senographe DMR) and the(More)