Silvia Llorente

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Occult hepatitis C virus (HCV) infection is a type of recently identified chronic infection that is evidenced only by detection of HCV RNA in liver; patients consistently test negative for antibodies to HCV and HCV RNA in serum. Using ex vivo and in vitro measures of T-cell responses, we have identified functional virus-specific memory CD4(+) and CD8(+) T(More)
Ontologies are a way to express semantics of concepts in a formal way. IPROnto is an ontology of the Digital Rights Management (DRM) domain. It has been specified to facilitate the development of e-commerce applications that need to be aware of rights associated to specific multimedia content. The paper describes the ontology and its possible uses. Since we(More)
Hepatitis C virus (HCV) RNA persistence in the liver has been described even after apparent resolution of HCV infection. Because T-cell reactivity plays a role in recovery from HCV infection, virus-specific T-cell responses were investigated in apparently recovered individuals in whom hepatic HCV RNA persistence was documented: 15 sustained virological(More)
BACKGROUND/AIMS Occult HCV infection has been described among anti-HCV-HCV RNA-negative individuals with abnormal transaminase values in whom HCV RNA is detected in liver. METHODS IgG antibody to an HCVcore-derived peptide (anti-HCVcore) was investigated in 145 patients with serologically silent occult HCV infection. RESULTS At the time of the(More)
The MPEG-21 Media Contract Ontology (MCO), a part of the standard ISO/IEC 21000, is an ontology to represent contracts dealing with rights on multimedia assets and intellectual property protected content in general. A core model provides the elements to describe the permissions, obligations and prohibitions exchanged in the clauses of a contract. Specific(More)
Regulatory ontologies combine ideas and results from different fields. Our approach to the topic is based on two aspects. First, the work we have done in the development of an ontology for Intellectual Property Rights (IPR), based on previous work done by our group and others. The second aspect is to apply these results to a new regulated area, that of the(More)
The management of electronic health records (EHR), in general, and clinical documents, in particular, is becoming a key issue in the daily work of Healthcare Organizations (HO). The need for providing secure and private access to, and storage for, clinical documents together with the need for HO to interoperate, raises a number of issues difficult to solve.(More)
The management of multimedia information is a key issue when permissions, protection issues and rights are involved. The appearance of new multimedia description formats, new distribution channels and diverse business models makes it difficult to provide a general solution for performing such management. In this scenario, the description of architectures(More)
The number of users of social networks (SN) has increased dramatically during the last years. In turn, the number of applications offered by SNs, as well as their usage by SN users, has also increased significantly. These applications are developed by third parties and access users' data to operate. This fact poses serious privacy risks, since SNs do not(More)