Silvia Comini

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The main objective of this study was to compare the anti-hypertensive efficacy and safety of nebivolol (5 mg once daily) and lisinopril (20 mg once daily) given for 12 weeks in patients with mild to moderate essential hypertension. Fourteen centres participated in this randomized, double-blind parallel group study. Sixty-eight patients with uncomplicated(More)
The interaction of beta-cyclodextrin (beta-CD) with four bile acids, cholic, taurocholic, chenodeoxycholic and lithocholic, was demonstrated by proton-NMR spectroscopy. Lithocholic and chenodeoxycholic acids exhibit a stronger affinity for beta-CD than cholic and taurocholic acids. The affinity of bile acids for beta-CD increases in relation to their(More)
In the industrial crystallisation process of maltitol (C(12)H(24)O(11)), the presence of maltotriitol (C(18)H(34)O(16)) in the maltose syrup is responsible for a change of the crystal morphology. Two different crystal forms of maltitol were obtained: a prismatic one and a 'bipyramidal' one. IR and X-ray diffraction experiments (single crystal and powder)(More)
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