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miR148b is a major coordinator of breast cancer progression in a relapse‐associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1
Breast cancer is often fatal during its metastatic dissemination. To unravel the role of microRNAs (miRs) during malignancy, we analyzed miR expression in 77 primary breast carcinomas and identifiedExpand
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Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity
Background Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathwayExpand
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New miRNA labeling method for bead-based quantification
BackgroundmicroRNAs (miRNAs) are small single-stranded non-coding RNAs that act as crucial regulators of gene expression. Different methods have been developed for miRNA expression profiling in orderExpand
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MicroRNA-27a Contributes to Rhabdomyosarcoma Cell Proliferation by Suppressing RARA and RXRA
Background Rhabdomyosarcomas (RMS) are rare but very aggressive childhood tumors that arise as a consequence of a regulatory disruption in the growth and differentiation pathways of myogenicExpand
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High IGFBP2 expression correlates with tumor severity in pediatric rhabdomyosarcoma.
Rhabdomyosarcoma (RMS) is the most common childhood sarcoma and is identified as either the embryonal or alveolar (ARMS) subtype. In approximately 75% of cases, ARMSs are characterized by specificExpand
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Integration Analysis of MicroRNA and mRNA Expression Profiles in Human Peripheral Blood Lymphocytes Cultured in Modeled Microgravity
We analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition, simulated by a ground-based rotating wall vessel (RWV) bioreactor. OurExpand
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miR-148b is a major coordinator in a relapse-associated miR signature in breast tumors
Reference EPFL-CONF-171224View record in Web of Science Record created on 2011-12-16, modified on 2017-05-12
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Genome-wide analysis of microRNA and gene expression profiles in human lymphocytes cultured in modeled microgravity during the DNA-damage response to γ-rays
Perturbations during the DNA-damage response (DDR) originated from alteration of the microRNA-mediated gene regulation can contribute to carcinogenesis initiation. We analyzed the expression profileExpand
Open Access METHODOLOGY ARTICLE
Background: microRNAs (miRNAs) are small single-stranded non-coding RNAs that act as crucial regulators of gene expression. Different methods have been developed for miRNA expression profiling inExpand