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  • Armando Santoro, Tiziana Pressiani, +11 authors Claudio Bordignon
  • Medicine
  • British Journal of Cancer
  • 2010 (First Published: 1 September 2010)
  • Background:Hepatocellular carcinoma (HCC) is a highly vascularised and poor-prognosis tumour. NGR-hTNF is a vascular-targeting agent consisting of human tumour necrosis factor-alpha fused to theContinue Reading
  • Nicola Personeni, Lorenza Rimassa, +13 authors Armando Santoro
  • Medicine
  • Clinical colorectal cancer
  • 2015 (First Published: 1 September 2015)
  • BACKGROUND Retrospective studies have suggested that phosphatase and tensin homolog (PTEN) expression might predict the efficacy of cetuximab in patients with KRAS wild-type metastatic colorectalContinue Reading
  • Filippo Pietrantonio, Rosalba Miceli, +23 authors Chiara Cremolini
  • Medicine
  • Annals of oncology : official journal of the…
  • 2016 (First Published: 17 November 2016)
  • Background Regorafenib and TAS-102 have recently demonstrated statistically significant survival gains in patients with refractory metastatic colorectal cancer (mCRC). Life expectancy ≥12 weeks wasContinue Reading
  • Nicola Personeni, Marina Baretti, +9 authors Lorenza Rimassa
  • Medicine
  • Gastric Cancer
  • 2016 (First Published: 1 May 2017)
  • BackgroundHER2 and topoisomerase 2 alpha (TOP2A) genomic status was previously reported to predict benefit from anthracyclines in breast cancer. We sought to define the prognostic impact and possibleContinue Reading
  • Lorenza Rimassa, Silvia Bozzarelli, +14 authors Armando Santoro
  • Medicine
  • Clinical colorectal cancer
  • 2019 (First Published: 1 February 2019)
  • BACKGROUND MET overexpression/amplification has been associated with resistance to anti- epidermal growth factor receptor therapies in patients with metastatic colorectal cancer (mCRC). CombiningContinue Reading