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The honeybee genome has substantially fewer protein coding genes ( approximately 11 000 genes) than Drosophila melanogaster ( approximately 13 500) and Anopheles gambiae ( approximately 14 000). Some of the most marked differences occur in three superfamilies encoding xenobiotic detoxifying enzymes. Specifically there are only about half as many(More)
Because of the widespread phenomenon of patrilocality, it is hypothesized that Y-chromosome variants tend to be more localized geographically than those of mitochondrial DNA (mtDNA). Empirical evidence confirmatory to this hypothesis was subsequently provided among certain patrilocal and matrilocal groups of Thailand, which conforms to the isolation by(More)
OBJECTIVES Bartonella bacilliformis is the aetiological agent of Carrion's disease. Although ciprofloxacin, rifampicin and erythromycin have been successfully used in the treatment of the disease, failures and relapses have been reported. The objective of our study was to select in vitro mutants resistant to antibiotics in order to determine the frequency(More)
BACKGROUND Whipple disease is a chronic infection caused by Tropheryma whipplei. Trimethoprim-sulfamethoxazole is recommended for treatment of Whipple disease but is associated with treatment failure. T. whipplei is resistant in vitro to trimethoprim, because the gene targeted by this agent is missing. METHODS A patient experienced clinical failure during(More)
Sir, Bartonella henselae are fastidious, facultative intracellular bacilli that can cause bacteraemia, endocarditis, cat-scratch disease in immunocompetent patients, and bacillary angiomatosis and peliosis hepatitis in immunocompromised patients. 1,2 There are a limited number of studies that have addressed the antibiotic treatment of cats infected with B.(More)
  • Damien Clarisse, Béatrice Pelotier, +11 authors N. Niranjan
  • 2011
Supplementary informations 1 H and 13 C NMR spectra were measured in CDCl 3 on a Bruker AC 300 or 400 spectrometers. Mass spectra were recorded on a Finigan-MAT 95 XL instrument; IR spectra were recorded on a Nicolet IR100. Melting points were measured with a B-540 Büchi. Column chromatography was carried out with silica gel 60A 40-63 μm (SDS). All the(More)
Antimicrobial treatments result in the host's enteric bacteria being exposed to the antimicrobials. Pharmacodynamic models can describe how this exposure affects the enteric bacteria and their antimicrobial resistance. The models utilize measurements of bacterial antimicrobial susceptibility traditionally obtained in vitro in aerobic conditions. However, in(More)
Ubiquitin (Ub), a protein consisting of 76 amino acid residues which is present in all eukaryotic cells tested (Rech-steiner, 1987), plays a role in the degradation of abnormal and short-lived proteins by the ATP-and Ub-dependent proteolytic systems (Hershko et al., 1980). Ubiquitination of histone 2A varies during the course of the cell cycle (Matsui et(More)
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