Silke Schäfer

Harald Staiger2
Fausto Machicao2
2Harald Staiger
2Fausto Machicao
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CONTEXT The voltage-gated potassium channel Kv1.3 (KCNA3) is expressed in a variety of tissues including liver and skeletal muscle. In animal models, knockout of Kv1.3 has been found to improve insulin sensitivity and glucose tolerance. OBJECTIVE We examined whether mutations in the Kv1.3 gene exist in humans and whether they are associated with(More)
  • Peter Weyrich, Harald Staiger, Alena Stančáková, Fausto Machicao, Jürgen Machann, Fritz Schick +6 others
  • 2010
BACKGROUND Toll-like-receptor 4 (TLR) is discussed to provide a molecular link between obesity, inflammation and insulin resistance. Genetic studies with replications in non-diabetic individuals in regard to their fat distribution or insulin resistance according to their carrier status of a common toll-like receptor 4 (TLR4) variant (TLR4(D299G/T399I)) are(More)
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