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BACKGROUND Multiple sclerosis (MS) is an autoimmune disease with known genetic and environmental susceptibility factors. Breastfeeding has been shown to be protective in other autoimmune diseases. OBJECTIVE This case-control study analyzed the association of breastfeeding in infancy on the risk of developing MS. METHODS A case-control study was(More)
Zahlreiche manualmedizinische Untersuchungen sind in der Praxis weit verbreitet. Für eine allgemeine Akzeptanz in klinischen Studien müssen diese Untersuchungen allerdings bestimmten psychometrischen Normen entsprechen. Bisher mangelt es an Belegen für die Reliabilität manualmedizinischer Untersuchungsverfahren. Der Zweck der vorliegenden Studie besteht in(More)
Sturge-Weber syndrome (SWS) is a neurocutaneous disorder characterized by cutaneous facial angioma, leptomeningeal angioma associated with seizures and other neurologic complications including mental retardation, and glaucoma. Only limited information about long-term outcome, including the societal integration of adult patients, is available in the(More)
Data were obtained on 171 individuals with Sturge-Weber syndrome via questionnaire and medical records. The age of the study group ranged from 2 months to 59 years; the median was 8 years. In addition to the facial location of port-wine stains in the areas of the trigeminal dermatomes present in 170 patients, 45% also had extracranial port-wine stains over(More)
BACKGROUND B cells and humoral immune responses play an important role in the pathogenesis and diagnosis of multiple sclerosis (MS). A characteristic finding in patients with MS is a polyspecific intrathecal B cell response against neurotropic viruses, specifically against measles virus, rubella virus, and varicella zoster virus, also known as an MRZ(More)
BACKGROUND Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) with increasing incidence mainly in high-income countries. One explanation of this phenomenon may be a higher prevalence of allergic and autoimmune diseases in industrialized countries as a consequence of otherwise beneficial advances in(More)
In Zeiten steigender Kosten ist es wichtig, die eigene Arbeit qualitativ hochwertig und nach aktuellen wissenschaftlichen Erkenntnissen auszuführen (evidenzbasierter Medizin). Der Augenmerk dieser Literaturrecherche liegt auf der Reliabilität manualmedizinischer Untersuchungen bei akutem Schmerz der Lendenwirbelsäule („low back pain“). Als Suchzeitraum(More)
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