Silene L S Pires

Learn More
These experiments examined whether the conscious sinoaortic baroreceptor-denervated (SAD) rat, owing to its high spontaneous arterial pressure (AP) variability, might represent a model for renal blood flow (RBF) autoregulation studies. In eight SAD and six baroreceptor-intact rats, AP and RBF were recorded (1-h periods) before and after furosemide (10 mg/kg(More)
The acute cardiovascular effects of an aqueous fraction of the ethanolic extract of the leaves (AFL) of Albizia inopinata (Harms) G. P. Lewis (Leguminosae) were studied in rats using a combined in vivo and in vitro approach. In conscious, unrestrained rats, AFL (5, 10 and 20 mg/kg(-1) body wt. i.v., randomly) produced a significant and dose-dependent(More)
It is often proposed that autoregulatory mechanisms prevent acute changes in systemic blood pressure (BP) from being transmitted to the glomerular capillary circulation. However, it is not known whether renal blood flow (RBF) is still autoregulated when the kidney is exposed to exaggerated BP fluctuations, in particular hypertensive episodes. The aim of the(More)
The cardiovascular effects of the aqueous fraction of the ethanol extract of the leaves (AFL) of Cissampelos sympodialis Eichl. were evaluated in this work. In conscious freely moving rats, AFL (0.5, 1, 2, 4 and 8 mg/kg, i.v.) increased the mean arterial pressure (MAP) by 7 ± 2,16 ± 5, 33 ± 5, 43 ± 3 and 38 ± 4 mmHg, respectively, followed by a significant(More)
  • 1