Learn More
Dendritic spines receive most excitatory inputs in the CNS. Recent evidence has demonstrated that the spine head volume is linearly correlated with the readily releasable pool of neurotransmitter and the PSD size. These correlations can be used to functionally interpret spine morphology. Using Golgi impregnations and light microscopy, we reconstructed 23000(More)
Dendritic protrusions are highly motile during postnatal development. Although spine morphological plasticity could be associated with synaptic plasticity, the function of rapid spine/filopodial motility is still unknown. To investigate the role of spine motility in the development of the visual cortex and its relation with critical periods, we used(More)
Dendritic spines and filopodia display actin-based morphological plasticity. The function of this rapid motility is unknown. Its ubiquitous expression during development has led to the hypothesis that motility plays a role in synaptogenesis. We investigated this by simultaneously imaging presynaptic boutons and dendritic protrusions in acute hippocampal(More)
  • 1