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Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
Among adults undergoing noncardiac surgery, MINS was an independent predictor of 30-day mortality and had the highest population-attributable risk of the perioperative complications.
pH effects on measurements of ionized calcium and ionized magnesium in blood.
The findings indicate that if adjustment to pH 7.40 is necessary, the ionized magnesium test results need to be adjusted when pH is markedly abnormal, as is sometimes done for ionized calcium.
Plasma interleukin-6 adds prognostic information in pulmonary arterial hypertension
This study enrolled patients with idiopathic, heritable, connective tissue-associated and congenital heart disease-associated PAH between March 2005 and June 2011 and determined if these inflammatory biomarkers add incremental prognostic information in PAH.
Sensitive measurement of serum 1α,25-dihydroxyvitamin D by liquid chromatography/tandem mass spectrometry after removing interference with immunoaffinity extraction.
Using immunoaffinity extraction enabled a sensitive LC/MS/MS method for quantification of 1α,25-dihydroxyvitamin D in serum, and it completely removed isobaric interferences and matrix effects present in patient serum.
Quality Control Practices for Chemistry and Immunochemistry in a Cohort of 21 Large Academic Medical Centers
Significant variation and unexpected similarities in practice across laboratories, including QC frequency, cutoffs, number of levels analyzed, and other features indicate an opportunity exists to establish an evidence-based approach to QC that can be generalized across institutions.
Breath analysis in pulmonary arterial hypertension.
Breathprint is different between patients with PAH and healthy control subjects, and several specific compounds, including ammonia, were elevated in the breath of patients withPAH.
Methylated arginine derivatives in children and adolescents with chronic kidney disease
BP load and a disproportionate elevation of SDMA are seen in children and adolescents with stage 2–3 chronic kidney disease (mild–moderate) CKD and SDMA is a strong marker for reduced eGFR and serves as a moderate but significant indicator of 24-hr BP load variability.
Epidemiology of vitamin D in health and disease
  • Sihe Wang
  • Medicine, Biology
    Nutrition Research Reviews
  • 28 October 2009
Results from ecological, case–control and cohort studies have shown that vitamin D reduces the risk of bone fracture, falls, autoimmune diseases, type 2 diabetes, CVD and cancer. However, there is
The MMACHC proteome: hallmarks of functional cobalamin deficiency in humans.