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Differential expression of somatostatin receptor subtypes in human peripheral blood mononuclear cell subsets.

• Elgin G. R. Lichtenauer-Kaligis, Virgil A. S. H. Dalm, +4 authors Leo J. Hofland
• European journal of endocrinology
• 2004

BACKGROUND Somatostatin (SS)-binding sites have been demonstrated in human lymphoid tissues and peripheral blood cells. However, not much is known with respect to the SS receptor subtype (sst)… (More)

Cytoplasmic tails of beta 1, beta 2, and beta 7 integrins differentially regulate LFA-1 function in K562 cells.

• Marijke Lub, Sandra J van Vliet, +4 authors Yvette van Kooyk
• Molecular biology of the cell
• 1997

The beta 2 integrin lymphocyte function-associated antigen 1 (LFA-1) mediates activation-dependent adhesion of lymphocytes. To investigate whether lymphocyte-specific elements are essential for LFA-1… (More)

Somatostatin is a selective chemoattractant for primitive (CD34(+)) hematopoietic progenitor cells.

• Sigrid P M A Oomen, Paula B. van Hennik, +5 authors Ivo P. Touw
• Experimental hematology
• 2002

OBJECTIVE Somatostatin (SST) is a regulatory peptide with a wide variety of activities in different tissues. SST activates G(alpha i)-protein-coupled receptors of a family comprising five members… (More)

Somatostatin receptors in the haematopoietic system.

• Sigrid P M A Oomen, Leo J. Hofland, P. Martin van Hagen, Steven W. J. Lamberts, Ivo P. Touw
• European journal of endocrinology
• 2000

Multiple interactions exist between the immune, haematopoietic, endocrine and nervous systems (1,2). The bi-directional communication between the immune/haematopoietic and nervous systems is mediated… (More)

Internalization-defective mutants of somatostatin receptor subtype 2 exert normal signaling functions in hematopoietic cells.

• Sigrid P M A Oomen, Leo J. Hofland, Steven W. J. Lamberts, Bob Löwenberg, Ivo P. Touw
• FEBS letters
• 2001

The regulatory peptide somatostatin (SST) acts via a family of G-protein-coupled receptors comprising five subtypes (SSTR1-5). G-protein-coupled receptors activate multiple signaling mechanisms,… (More)

Somatostatin modulates G-CSF-induced but not interleukin-3-induced proliferative responses in myeloid 32D cells via activation of somatostatin receptor subtype 2.

• Sigrid P M A Oomen, Alister C Ward, Leo J. Hofland, Steven W. J. Lamberts, Bob Löwenberg, Ivo P. Touw
• The hematology journal : the official journal of…
• 2001

INTRODUCTION Somatostatin, originally identified as a peptide involved in neurotransmission, functions as an inhibitor of multiple cellular responses, including hormonal secretion and proliferation.… (More)

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