Sigbjørn O Rogne

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BACKGROUND AND PURPOSE There are indications that vitamin D may be important for more than skeletal health, including cognitive function. METHODS The study was performed in Tromsø, Northern Norway (The Tromsø Study). In a cross-sectional study serum 25-hydroxyvitamin D (25(OH)D) was measured and cognitive function (word recall, digit-symbol coding, finger(More)
BACKGROUND/AIMS Late-onset Alzheimer's disease (LOAD) comprises sporadic LOAD and familial LOAD. We wanted to determine whether total plasma homocysteine (Hcy), cardiovascular risk factors and volumetric analyses of cerebral magnetic resonance imaging (MRI) were differently associated with mild cognitive impairment (MCI) in subjects from families with(More)
BACKGROUND/AIMS Albuminuria and carotid atherosclerosis are predictors of cardiovascular disease and potential predictors of cognitive decline. Our aim was to study whether albuminuria was an early predictor of cognitive function independent of carotid atherosclerosis in a general population. METHODS The study population comprised 1,577 adults without(More)
BACKGROUND/AIMS Subjective memory complaints (SMC) are strong predictors of mild cognitive impairment (MCI) and subsequent Alzheimer's disease. Our aims were to see if fully automated cerebral MR volume measurements could distinguish subjects with SMC and MCI from controls, and if probable parental late-onset Alzheimer's disease (LOAD), apolipoprotein E ε4(More)
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