Siegfried Wagner

Ingo Nolte6
Hugo Murua Escobar6
6Ingo Nolte
6Hugo Murua Escobar
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Current market research indicates high future demand for broadcast services such as Mobile TV. While underlying competing bearer technologies are being extensively tested and refined, the focus keeps shifting towards interactive services on top of mobile broadcast. In order to investigate the possibilities of interactive mobile TV, projects require testbeds(More)
Access to information and communication using the Internet is still very limited for people with poor reading skills. Current mainstream web-applications such as email or web-shops are designed for people that have good reading skills. In our research we investigated the use of a web based email system by people with poor reading and writing skills. As(More)
Conventional two-dimensional (2-D) texture parameters serve as the "gold standard" of texture analysis. The authors compared a new stochastic model, based on autoregressive periodic random field models (APRFM) with conventional texture analysts (CTA) parameter, which were defined as measures of the co-occurrence matrix, i.e., entropy, contrast, correlation,(More)
BACKGROUND In molecular medicine, the manipulation of cells is prerequisite to evaluate genes as therapeutic targets or to transfect cells to develop cell therapeutic strategies. To achieve these purposes it is essential that given transfection techniques are capable of handling high cell numbers in reasonable time spans. To fulfill this demand, an(More)
The discovery of the post-transcriptional gene silencing (PTGS) by small non-protein-coding RNAs is considered as a major breakthrough in biology. In the last decade we just started to realize the biologic function and complexity of gene regulation by small non-coding RNAs. PTGS is a conserved phenomenon which was observed in various species such as fungi,(More)
Ultrashort pulsed laser ablation in liquids represents a powerful tool for the generation of pure gold nanoparticles (AuNPs) avoiding chemical precursors and thereby making them especially interesting for biomedical applications. However, because of their electron accepting properties, laser-generated AuNPs might affect biochemical properties of(More)
Prostate cancer is worldwide the sixth leading cause of cancer related death in men thus early detection and successful treatment are still of major interest. The commonly performed screening of the prostate-specific antigen (PSA) is controversially discussed, as in many patients the prostate-specific antigen levels are chronically elevated in the absence(More)
  • Saskia Willenbrock, Siegfried Wagner, Nicola Reimann-Berg, Mohammed Moulay, Marion Hewicker-Trautwein, Ingo Nolte +1 other
  • 2014
The architectural transcription factor HMGA2 is abundantly expressed during embryonic development. In several malignant neoplasias including prostate cancer, high re-expression of HMGA2 is correlated with malignancy and poor prognosis. The let-7 miRNA family is described to regulate HMGA2 negatively. The balance of let-7 and HMGA2 is discussed to play a(More)
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