Sidney Coleman

Learn More
~4Y. Nambu and G. Jona-Lasino, Phys. Rev. 122, 345 (1961); S. Coleman and E. Weinberg, Phys. Rev. D 7, 1888 (1973). ' K. Symanzik (to be published) has recently suggested that one consider a A. @4 theory with a negative A, to achieve UV stability at A=0. However, one can show, using the renormalization-group equations, that in such theory the ground-state(More)
A single gene (Prn-i) that affects scrapie incubation period in mice has been identified. I/LnJ mice have a very long incubation period after inoculation of scrapie prions (200-385 days) and NZW/LacJ mice have a short one (113 +/- 2.8 days). (NZW X I/Ln)F1 hybrid mice had incubation times of 223 +/- 2.8 days indicating longer incubation times were dominant.(More)
Epidermal growth factor (EGF) is a potent mitogen for a variety of cells in vitro, but studies on its effects in vivo and its possible role as a natural growth regulator are few. Using slow-release plastic implants, capable of delivering EGF to small regions of the gland over a period of several days, we have shown that EGF reinitiated ductal growth and(More)
Exogenous transforming growth factor beta (TGF-beta 1) was shown in earlier studies to reversibly inhibit mouse mammary ductal growth. Using small plastic implants to treat regions of developing mammary glands in situ, we now report that TGF-beta 1 growth inhibition is associated with an ectopic accumulation of type I collagen messenger RNA and protein, as(More)
In culture, cAMP is known to be mitogenic for mammary cells and several other epithelia, but evidence for a similar role in vivo has been only correlative. We have used plastic implants to cause slow release of cholera toxin and other cAMP-active agents to local areas of mammary glands in ovariectomized mice. Elevated levels of intracellular cAMP around the(More)
A black hole may carry quantum numbers that are not associated with massless gauge fields, contrary to the spirit of the “no-hair” theorems. We describe in detail two different types of black hole hair that decay exponentially at long range. The first type is associated with discrete gauge charge and the screening is due to the Higgs mechanism. The second(More)
As lead is phased out of gasoline, other additives with anti-knock properties, particularly organic manganese compounds, are being substituted. Unavoidably, such compounds go through the combustion process, are eliminated in exhaust gases, and become part of the city environment. To obtain some indication of the extent of this new pollution street soils(More)
EGF, initially demonstrated to be a potent mitogen for a variety of cell types, has more recently been shown to inhibit proliferation of several cell lines. Few studies, however, have addressed the effects of EGF on growth and morphogenesis of tissues in vivo, particularly with regard to EGF as a possible inhibitor. We now demonstrate that EGF treatment of(More)
“The Euclidean formulation of gravity is not a subject with firm foundations and clear rules of procedure; indeed it is more like a trackless swamp. I think I have threaded my way through it safely, but it is always possible that unknown to myself I am up to my neck in quicksand and sinking fast.” Sidney Coleman