Siddharth Vikal

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With MRI possibly becoming a modality of choice for detection and staging of prostate cancer, fast and accurate outlining of the prostate is required in the volume of clinical interest. We present a semi-automatic algorithm that uses a priori knowledge of prostate shape to arrive at the final prostate contour. The contour of one slice is then used as(More)
MOTIVATION Image-guided percutaneous (through the skin) needle-based surgery has become part of routine clinical practice in performing procedures such as biopsies, injections and therapeutic implants. A novice physician typically performs needle interventions under the supervision of a senior physician; a slow and inherently subjective training process(More)
A slice-to-volume registration algorithm, to be used for prostate tracking, is presented. The technique is designed to provide patient tracking information for prostate biopsy performed under MR guidance. Interventional MR slices are acquired from a static physical plane just prior to needle insertion. These slices are registered to a high resolution volume(More)
We report a quantitative evaluation of the clinical accuracy of a MRI-guided robotic prostate biopsy system that has been in use for over five years at the U.S. National Cancer Institute. A two-step rigid volume registration using mutual information between the pre and post needle insertion images was performed. Contour overlays of the prostate before and(More)
PURPOSE Infective keratitis is a major sight-threatening condition in developing countries like India. An early diagnosis of infective keratitis is critical to its treatment. Epidemiological trends, morphological features of corneal ulceration and presence of other risk factors often dictate choice of initial treatment. This work assesses the usefulness of(More)
UNLABELLED Prostate cancer is a major health threat for men. For over five years, the U.S. National Cancer Institute has performed prostate biopsies with a magnetic resonance imaging (MRI)-guided robotic system. PURPOSE A retrospective evaluation methodology and analysis of the clinical accuracy of this system is reported. METHODS Using the pre and(More)
Ultrasound has become a very important modality in image-guided therapy. At present, however, the collection, synchronization and transfer of ultrasonic images are more cumbersome than necessary. This paper presents a reusable solution to these problems. We propose a software package called SynchroGrab, which allows the collection of interventional(More)
Computer aided diagnosis (CAD) of cancerous anatomical structures via 3D medical images has emerged as an intensively studied research area. In this paper, we present a principled three-tiered image feature learning approach to capture task specific and data-driven class discriminative statistics from an annotated image database. It integrates voxel-,(More)
PURPOSE Brachytherapy (radioactive seed insertion) has emerged as one of the most effective treatment options for patients with prostate cancer, with the added benefit of a convenient outpatient procedure. The main limitation in contemporary brachytherapy is faulty seed placement, predominantly due to the presence of intra-operative edema (tissue(More)
Image-guided percutaneous needle-based surgery has become part of routine clinical practice in performing procedures such as biopsies, injections and therapeutic implants. A novice physician typically performs needle interventions under the supervision of a senior physician; a slow and inherently subjective training process that lacks objective,(More)