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Control in power systems that may be vulnerable to security attacks is discussed in this paper as are control loop vulnerabilities, potential impact of disturbances, and several mitigations. ABSTRACT | The development of a trustworthy smart grid requires a deeper understanding of potential impacts resulting from successful cyber attacks. Estimating feasible(More)
—The development of a smarter electric grid will depend on increased deployments of information and communication technology (ICT) to support novel communication and control functions. Unfortunately, this additional dependency also expands the risk from cyber attacks. Designing systems with adequate cyber security depends heavily on the availability of(More)
Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal antibodies against CD20 or kinase inhibitors during the past 2 years. Clinicians should be aware of this emerging(More)
Meeting current demands for critical infrastructure cyber security education and research will require accurate testbed development. The PowerCyber was designed to closely resemble power grid communication utilizing actual field devices and SCADA software. The testbed provides a novel environment where students can explore cyber attacks and defenses while(More)
Burkholderia pseudomallei is an emerging pathogen that causes melioidosis, a serious and potentially fatal disease which requires prolonged antibiotics to prevent relapse. However, diagnosis of melioidosis can be difficult, especially in culture-negative cases. While metabolomics represents an uprising tool for studying infectious diseases, there were no(More)
To identify potential biomarkers for improving diagnosis of melioidosis, we compared plasma metabolome profiles of melioidosis patients compared to patients with other bacteremia and controls without active infection, using ultra-high-performance liquid chromatography-electrospray ionization-quadruple time-of-flight mass spectrometry. Principal component(More)
  • Jasper Fuk-Woo Chan, Cyril Chik-Yan Yip, Jessica Oi-Ling Tsang, Kah-Meng Tee, Jian-Piao Cai, Kenn Ka-Heng Chik +13 others
  • 2016
Zika virus (ZIKV) is unique among human-pathogenic flaviviruses by its association with congenital anomalies and trans-placental and sexual human-to-human transmission. Although the pathogenesis of ZIKV-associated neurological complications has been reported in recent studies, key questions on the pathogenesis of the other clinical manifestations,(More)
BACKGROUND Neuromyelitis optica (NMO) is an autoimmune inflammatory condition of the central nervous system that is characterized by circulating anti-aquaporin-4 antibodies, transverse myelitis and optic neuritis. NMO spectrum disorders are rarely reported in patients with active pulmonary tuberculosis (TB). We report a fatal case of anti-aquaporin-4(More)
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