Si-Yeol Kim

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Calcium-binding proteins are thought to play important roles in calcium buffering. The present study investigated the effects of ischemia and reperfusion on calbindin D28K, calretinin, and parvalbumin immunoreactivity in the ganglion cell layer of the rabbit. Rabbits were administered ischemic damage by increasing the intraocular pressure. After 60 and 90(More)
We studied the effects of monocular enucleation on the patterned distribution of calretinin-, calbindin D28K- and parvalbumin-immunoreactive (IR) neurons in the superficial layers of the hamster superior colliculus (SC). The calcium-binding proteins were localized using antibody immunocytochemistry. Almost complete depletion of the calretinin-IR fibers in(More)
We recently reported on the distribution and effects of eye enucleation on the immunoreactivity of calretinin in the superficial layers of the hamster superior colliculus (SC). In the present study, we describe the types of labeled cells and compare this labeling to that of GABA, the major inhibitory neurotransmitter in the central nervous system. An almost(More)
We developed a disposable electrode for the electroretinogram made of anomalous polyvinyl alcohol gel. This new hydrogel is a rubber-like elastic with water content 80–90 wt%, but insoluble in water. The elastic electrode plate is approximately 0.3–1.0mm thick, sterile, flexible, and easily cut to the desired shape. Its low cost permits it to be discarded(More)
The purpose of this study was to evaluate the efficacy and safety of biodegradable intrascleral implants for the slow release of triamcinolone acetonide (TA). Intrascleral implant (1 mm thick; 3 mm diameter) was made of PLA (poly(D,L-lactide)) containing 6.4 mg of TA with one-side coating of high molecular weight PLA to render unidirectional drug absorption(More)
We examined some of the problems arising when c-waves are employed in pharmacological experiments with pigmented rabbits. The cyclic variations of the c-wave are smaller in rabbit than in other species. Under our experimental conditions the c-wave amplitudes in some rabbits reached an equilibrium under intermittent stimuli, while in others they increased(More)
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