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BACKGROUND The second wave of avian influenza H7N9 virus outbreak in humans spread to the Guangdong province of China by August of 2013 and this virus is now endemic in poultry in this region. METHODS Five patients with H7N9 virus infection admitted to our hospital during August 2013 to February 2014 were intensively investigated. Viral load in the(More)
Structured programming principles are not strong enough to control complexity and guarantee high reliability of software at the module level. Stronger organizing principles and stronger properties of components are needed to make significant gains in the quality of software. Practical proposals, based on the definition of normal forms which have a(More)
Loops with multiple-exits and flags detract from the quality of imperative programs. They tend to make control-structures difficult to understand and, at the same time, introduce the risk of non-termination and other correctness problems. A systematic, generally applicable procedure, called loop rationalization, which removes such features and simplifies(More)
Goto statements detract from the quality of imperative programs. They tend to make control-structures difficult to understand and, at the same time, introduce the risk of non-termination and other correctness problems. A new, formal, generally applicable procedure, for removing all goto statements from program structures is presented. This method, is based(More)
The cost of developing and maintaining high quality software remains at a premium. In this paper we introduce a practical approach for enhancement of software quality, based on calculation of strongest postconditions of program components. The method provides a powerful means for detecting and removing by transformation various forms of redundancy and(More)
BACKGROUND Since the identification in early 2013 of severe disease caused by influenza A(H7N9) virus infection, there have been few attempts to characterize the full severity profile of human infections. Our objective was to estimate the number and severity of H7N9 infections in Guangzhou, using a serological study. METHODS We collected residual sera(More)
BACKGROUND Influenza A(H1N1)pdm09, A(H3N2) and B viruses have co-circulated in the human population since the swine-origin human H1N1 pandemic in 2009. While infections of these subtypes generally cause mild illnesses, lower respiratory tract infection (LRTI) occurs in a portion of children and required hospitalization. The aim of our study was to estimate(More)
There is increasing evidence that nicotine is involved in learning and memory. However, there are only few studies that have evaluated the relationship between nicotine and memory reconsolidation. In this study, we investigated the effects of nicotine on the reconsolidation of novel object recognition memory in rats. Behavior procedure involved four(More)
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