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We use supersonic shear wave imaging (SSI) technique to measure not only the linear but also the nonlinear elastic properties of brain matter. Here, we tested six porcine brains ex vivo and measured the velocities of the plane shear waves induced by acoustic radiation force at different states of pre-deformation when the ultrasonic probe is pushed into the(More)
Dynamic elastography has become a new clinical tool in recent years to characterize the elastic properties of soft tissues in vivo, which are important for the disease diagnosis, e.g., the detection of breast and thyroid cancer and liver fibrosis. This paper investigates the supersonic shear imaging (SSI) method commercialized in recent years with the(More)
Juvenile xanthogranuloma is a benign histiocytic skin disorder encountered primarily in infancy and childhood. Approximately 0.4% of cases exhibit ocular manifestations, which can result in glaucoma and blindness. We present a case of a 7-month-old male with unilateral glaucoma associated with Juvenile xanthogranuloma, and emphasize the importance of an(More)
PURPOSE Human skin consists of several layers including epidermis, dermis, and hypodermis. The determination of the in vivo mechanical properties of an individual skin layer represents a great challenge to date. In this study, the authors explore the use of the supersonic shear imaging (SSI) technique and inverse analysis to determine the in vivo elastic(More)
The goal of the work described here was to explore the cause of spleen stiffness (SS) in hepatic fibrogenesis and evaluate the value of SS in liver fibrosis (LF) staging. LF was induced with carbon tetrachloride (CCl4) in rats (n = 40). Supersonic shear wave imaging and contrast-enhanced ultrasound were performed to determine liver stiffness (LS), SS and(More)
AIM To evaluate the correlation of shear wave elastography (SWE) results with liver fibrosis histology and quantitative function reserve. METHODS Weekly subcutaneous injection of 60% carbon tetrachloride (1.5 mL/kg) was given to 12 canines for 24 wk to induce experimental liver fibrosis, with olive oil given to 2 control canines. At 24 wk, liver condition(More)
OBJECTIVE To investigate the expressions of CD1a and CD83 of Langerhans cells (LC) in the lesions of epidermodysplasia verruciformis (EV) patients. METHODS We used immunohistochemical method to detect the expressions of CD1a and CD83 in the lesions of 10 patients with EV lesions and in the skins of 10 normal subjects. RESULTS No CD83 + LCs was detected(More)
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