Shyam Sundar Sharma

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The purpose of this study was to determine the effect of gender on changes in electromyographic (EMG) signal characteristics of the quadriceps muscles with increasing force and with fatigue. A total of fourteen healthy adults (seven men, seven women) participated in the study. Subjects had to perform isometric ramp contractions in knee extension with the(More)
The effect of drug acting on 5-HT1A, 5-HT2 and 5-HT3 receptors were studied against cisplatin and apomorphine induced emesis in dogs. Buspirone, 5-HT1A receptor partial agonist significantly reduced the emetic episodes though it had no significant effect on emetic latency. Mianserin, 5-HT2 receptor antagonist exhibited significant reduction in emetic(More)
Involvement of p53 has been implicated in apoptosis induced cell death in ischemic reperfusion injury. In the present study, we have investigated neuroprotective potential of pifithrin-alpha, a p53 inhibitor in bilateral common carotid arteries occlusion (5 min) model of global cerebral ischemia in Mongolian gerbils. Gerbils were treated with(More)
We are reporting 12 cases of traumatic bilateral extradural haematomas. The incidence was 4.8% of all cases of extradural haematomas. The most common site was the frontal region. CT scan examination was necessary for early diagnosis. Ten patients were operated upon while one patient was treated conservatively. Two patients died. The relevant literature is(More)
Hippophae rhamnoides L. belonging to family Elaeagnaceae has been a species of interest due to its high nutritional value. In the present study, a set of 26 novel microsatellites from Hippophae developed from an enriched genomic library using biotin labelled di, tri and tetra nucleotide repeats have been reported. Out of 108 clones sequenced, only 62(More)
Oil content and fatty acid composition were studied in developing seeds of Pongamia, at intervals of 30 days starting from 45 days after anthesis up to 255 days after anthesis. The oil content increased from 15.96 to 36.93 % as the seed matured. A significant variation in fatty acid composition of the oil was detected during seed development. Proportion of(More)
North eastern (NE) India harbours a precious germplasm repository of Capsicum in the form of various landraces. The present study was undertaken to characterise the extent of genetic variation present in different Capsicum landraces from north eastern India. A set of 171 Capsicum accessions were characterised using three-endonuclease amplified fragment(More)
BACKGROUND Lysine-specific demethylase 1 (LSD1 or KDM1A) overexpression correlates with poor survival and castration resistance in prostate cancer. LSD1 is a coregulator of ligand-independent androgen receptor signaling promoting c-MYC expression. We examined the antitumor efficacy of LSD1 inhibition with HCI-2509 in advanced stages of prostate cancer. (More)
The authors compared the utility of two variants of Amplified Fragment Length Polymorphism (AFLP) technique, viz. 4-selective AFLP and three Endonuclease Amplified Fragment Length Polymorphism (TE-AFLP), for accurate assessment of genetic diversity in tea. These assays were optimized to resolve the reported discrepancies in detected levels of genetic(More)