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The growth factor GM-CSF has an important role in pulmonary surfactant metabolism and the regulation of antibacterial activities of lung sentinel cells. However, the potential of intra-alveolar GM-CSF to augment lung protective immunity against inhaled bacterial pathogens has not been defined in preclinical infection models. We hypothesized that transient(More)
BACKGROUND Current protocols for detection of circulating fibrocytes (CFs) in peripheral blood described in various pulmonary and nonpulmonary disorders involve complex and time consuming, non standardized techniques. OBJECTIVE Testing a method to rapidly detect and quantify CFs using whole blood lysis flow cytometry-based assay in patients with(More)
Significant pericardial effusions are an uncommon but very important disorder in childhood. In our patient, cross-sectional imaging demonstrated a massive pericardial effusion. The underlying etiology here was connective tissue disease causing recurrent pericardial effusion. An associated left-sided pleural effusion was noted. Clinicians must be aware of(More)
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