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  • Yanli Qin, Ji-ming Zhang, +6 authors Shuping Tong
  • Biology, Medicine
  • Journal of medical virology
  • 2009 (First Publication: 1 May 2009)
  • The A1762T and G1764A mutations in the basal core promoter (BCP) region and the G1896A mutation in the precore (PC) region of hepatitis B virus (HBV) genome are found commonly in HBeAg-negativeContinue Reading
  • Karen Kwei, Xuhua Tang, +5 authors Shuping Tong
  • Biology, Medicine
  • Journal of virology
  • 2013 (First Publication: 15 February 2013)
  • Hepatitis B virus immune escape mutants have been associated with vaccine failure and reinfection of grafted liver despite immune prophylaxis, but their biological properties remain largely unknown.Continue Reading
  • Yuehua Huang, Andrew W Tai, Shuping Tong, Anna Suk-Fong Lok
  • Biology, Medicine
  • Journal of hepatology
  • 2013 (First Publication: 1 June 2013)
  • BACKGROUND & AIMS Hepatitis B virus (HBV) core promoter (CP) mutations have been associated with an increased risk of hepatocellular carcinoma (HCC) in clinical studies. We previously reported that aContinue Reading
  • Danielle Gutelius, Jisu Li, Jack R Wands, Shuping Tong
  • Biology, Medicine
  • Journal of virology
  • 2011 (First Publication: 15 December 2011)
  • The pregenomic RNA (pgRNA) of hepatitis B virus (HBV) serves as the messenger for both core and P proteins, with the downstream P gene translated by ribosomal leaky scanning. HBV replication beginsContinue Reading
  • Eun Kim, Ke Li, +6 authors Jisu Li
  • Biology, Medicine
  • Journal of hepatology
  • 2008 (First Publication: 1 November 2008)
  • BACKGROUND/AIMS We previously reported that hepatitis C virus (HCV) core protein up regulated transcription of apolipoprotein C-IV (ApoC-IV, 10.7-fold increase), a member of the apolipoprotein familyContinue Reading
  • Li Zong, Yanli Qin, +6 authors Jisu Li
  • Medicine, Biology
  • Virology
  • 2017 (First Publication: 1 May 2017)
  • Hepatitis B virus (HBV) transcribes two subsets of 3.5-kb RNAs: precore RNA for hepatitis B e antigen (HBeAg) expression, and pregenomic RNA for core and P protein translation as well as genomeContinue Reading
  • Koichi Watashi, Guoxin Liang, +14 authors Takaji Wakita
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2013 (First Publication: 1 November 2013)
  • Virus infection is restricted by intracellular immune responses in host cells, and this is typically modulated by stimulation of cytokines. The cytokines and host factors that determine the host cellContinue Reading