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  • Eric L. Greer, Travis J. Maures, Anna G. Hauswirth, Erin M. Green, Dena S. Leeman, Géraldine S. Maro +4 others
  • 2010
The plasticity of aging suggests that longevity may be controlled epigenetically by specific alterations in chromatin state. The link between chromatin and aging has mostly focused on histone deacetylation by the Sir2 family 1 , 2 , but less is known about the role of other histone modifications in longevity. Histone methylation plays a crucial role during(More)
— The paper describes an indoor helicopter testbed that allows implementing and testing of bio-inspired control algorithms developed from scientific studies on insects. The helicopter receives and is controlled by simulated sensory inputs (e.g. visual stimuli) generated in a virtual 3D environment, where the connection between the physical world and the(More)
—Many resource allocation problems can be formulated as an optimization problem whose constraints contain sensitive information about participating users. This paper concerns solving this kind of optimization problem in a distributed manner while protecting the privacy of user information. Without privacy considerations, existing distributed algorithms(More)
— We consider the problem of purely visual pose stabilization (also known as servoing) of a second-order rigid-body system with six degrees of freedom: how to choose forces and torques, based on the current view and a memorized goal image, to steer the pose towards a desired one. Emphasis has been given to the bio-plausibility of the computation, in the(More)
— We consider the problem of attitude stabilization using exclusively visual sensory input, and we look for a solution which can satisfy the constraints of a " bio-plausible " computation. We obtain a PD controller which is a bilinear form of the goal image, and the current and delayed visual input. Moreover, this controller can be learned using classic(More)
We report the narrowest to-date (21 gauge, 820-microm-diam) handheld forward-imaging optical coherence tomography (OCT) needle endoscope and demonstrate its feasibility for ophthalmic OCT inspection. The probe design is based on paired-angle-rotation scanning (PARS), which enables a linear B-scan pattern in front of the probe tip by using two(More)
  • Mounia Tannour-Louet, Shuo Han, Sean T. Corbett, Jean-Francois Louet, Svetlana Yatsenko, Lindsay Meyers +4 others
  • 2010
Disorders of sexual development (DSD), ranging in severity from genital abnormalities to complete sex reversal, are among the most common human birth defects with incidence rates reaching almost 3%. Although causative alterations in key genes controlling gonad development have been identified, the majority of DSD cases remain unexplained. To improve the(More)
—We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have access to time series data describing the evolution of the spreading process observed by a collection of sensor nodes(More)
—How does one evaluate the performance of a stochastic system in the absence of a perfect model (i.e. probability distribution)? We address this question under the framework of optimal uncertainty quantifica-tion (OUQ), which is an information-based approach for worst-case analysis of stochastic systems. We are able to generalize previous results and show(More)
Genistein (4', 5, 7-trihydroxyisoflavone) is an isoflavone compound obtained from plants that has potential applications in cancer therapy. However, the molecular mechanism of the action of genistein on cancer cell apoptosis is not well known. In this study, we investigated the effect of genistein on topoisomerase II-alpha (Topo IIalpha), an important(More)