Shunya Takahashi

Yayoi Hongo2
Arata Yajima1
Masao Ohnishi1
Yoshikage Muroi1
2Yayoi Hongo
1Arata Yajima
1Masao Ohnishi
1Yoshikage Muroi
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Lysophospholipids are important signaling molecules in animals and metazoan cells. They are widely distributed among marine invertebrates, where their physiological roles are unknown. Sea cucumbers produce unique lysophospholipids. In this study, two lysophospholipids were detected in Holothuria atra for the first time, lyso-platelet activating factor and(More)
This report describes that a regular positive electrospray ionization mass spectrometry (MS) analysis of terpendoles often causes unexpected oxygen additions to form [M + H + O](+) and [M + H + 2O](+), which might be a troublesome in the characterization of new natural analogues. The intensities of [M + H + O](+) and [M + H + 2O](+) among terpendoles were(More)
  • Yasukiyo Yoshioka, Yue Qi Ye, Kiyoshi Okada, Kayoko Taniguchi, Ayaka Yoshida, Kouichi Sugaya +6 others
  • 2013
Tumor necrosis factor alpha (TNF-α), a central mediator of the inflammatory response, is released from basophilic cells and other cells in response to a variety of proinflammatory stimuli. Vialinin A is a potent inhibitor of TNF-α production and is released from RBL-2H3 cells. Ubiquitin-specific peptidase 5 (USP5), a deubiquitinating enzyme, was identified(More)
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