• Publications
  • Influence
A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery.
Doxorubicin (DOX) is one of the most effective anti-cancer drugs, but its therapeutic efficacy is greatly hampered by its non-specific delivery to the target tissue and the resultant cumulativeExpand
  • 147
  • 3
Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex.
Adriamycin (ADM) has been effective against many types of solid tumors in clinical applications. However, its use is limited because of systemic toxicities, primarily cardiotoxicity, and multidrugExpand
  • 44
  • 1
A paclitaxel-conjugated adenovirus vector for targeted drug delivery for tumor therapy.
Tumor-targeted drug delivery is an attractive strategy in cancer treatment. Our previous study demonstrated that modified adenovirus has strong tumor targeting ability and less toxicity toExpand
  • 41
  • 1
Synthesis of a Novel l-Methyl-Methionine–ICG-Der-02 Fluorescent Probe for In Vivo Near Infrared Imaging of Tumors
PurposeA novel near infrared fluorescent probe, l-methyl-methionine (Met)–ICG-Der-02, was synthesized and characterized for in vivo imaging of tumors and early diagnosis of cancers.MethodMet wasExpand
  • 16
  • 1
Fast clearing RGD-based near-infrared fluorescent probes for in vivo tumor diagnosis.
A fast clearing hydrophilic near-infrared (NIR) dye ICG-Der-02 was used to constitute tumor targeting contrast agents. Cell adhesion molecule integrin α(v)β(3) served as the target receptor becauseExpand
  • 37
A fast tumor-targeting near-infrared fluorescent probe based on bombesin analog for in vivo tumor imaging.
Bombesin (BBN), an analog of gastrin-releasing peptide (GRP), of which the receptors are over-expressed on various tumor cells, is able to bind to GRP receptor specifically. In this study, aExpand
  • 7
Near Infrared Fluorescent Probe Based on Bombesin Analogue for Tumor Diagnosis in vivo
Gastrin-releaing peptide(GRP) receptors have over expression distribution on several type of human tumors and less distribution in health tissue. As an GRP analogue, 14 amino acid residues, bombesinExpand
Synthesis of dimeric cyclic RGD based near-infrared probe for in vivo tumor diagnosis
  • J. Cao, Shunan Wan, +5 authors Y. Gu
  • Engineering, Physics
  • Photonics West - Biomedical Optics
  • 9 February 2012
Cell adhesion molecule integrin αvβ3 is an excellent target for tumor interventions because of its unique expression on the surface of several types of solid tumor cells and on almost all sproutingExpand
  • 1
Synthesis and characterization of NIR light-responsive LbL nanocapsules
In this paper, near-infrared (NIR) light responsive polyelectrolyte multilayer capsules (PE/Au NRs@Dox) were successfully synthesized by layer-by-layer techniques. Gold nanorods with aspect ratio ofExpand