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A set of k-principal points (Flury, 1990) of the distribution of a p-dimensional random vector X is defined as a set of k points in R p that minimizes the mean squared distance M SD ∥X − γ j ∥ 2 ]. A set of k-principal points provides an optimal k-point-approximation of the distribution and is a generalization of the mean E[X] from one point to k points.… (More)

The simple repetitive control system proposed by Yamada et al. is a type of servomechanism for the periodic reference input. That is, the simple repetitive control system follows the periodic reference input with small steady state error, even if a periodic disturbance or uncertainty exists in the plant. In addition, simple repetitive control systems make… (More)

R-spondin (RSPO) gene fusions have recently been discovered in a subset of human colorectal cancer (CRC) in the U.S. population; however, whether the fusion is recurrent in CRC arising in patients from the other demographic areas and whether it is specific for CRC remain uncertain. In this study, we examined 75 primary CRCs and 121 primary lung cancers in… (More)

Mitosis is the most conspicuous cell cycle phase and Shugoshin-like 1 (SGOL1) is a key protein in protecting sister chromatids from precocious separation during mitosis. We studied the role of SGOL1 and its splice variants in non-small cell lung cancer (NSCLC) using 82 frozen NSCLC tissue samples. SGOL1-B expression was prevalent in smokers, in cases with a… (More)

- Tatsuya Sakanushi, Kou Yamada, Iwanori Murakami, Yoshinori Ando, Takaaki Hagiwara, Shun Matsuura +1 other
- 2012

The simple repetitive control system proposed by Yamada et al. is a type of servomechanism for periodic reference input. Thus, the simple repetitive control system follows a periodic reference input with small steady-state error, even if there is periodic disturbance or uncertainty in the plant. In addition, simple repetitive control systems ensure that… (More)

Gaussian random function is a random function whose values are normally distributed and has some good properties (e.g., Lifshits [2], Tarpey and Kinateder [5], Shimizu and Mizuta [4]). In this presentation, we discuss hypothesis testing for multivariate Gaussian random function. A random function can be viewed as an infinite (p = ∞) dimensional random… (More)

The fusion gene echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) is identified in approximately 5% of non-small-cell lung cancer patients. A rare case of ALK-positive squamous cell carcinoma of the lung is reported. A 60-year-old man, an ex-smoker with a 720-packs-per-year tobacco smoking history, presented with a… (More)