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Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress
Reticulon3 (RTN3), firstly isolated from the retina and widely expressed in human tissues with the highest expression in the brain, is presumed to play an important role in the developing axonsExpand
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Nogo-B promotes the epithelial-mesenchymal transition in HeLa cervical cancer cells via Fibulin-5.
Cervical cancer is a common malignancy in women worldwide, and the occurrence of invasion and metastasis is the major cause for most cancer-related deaths. Expand
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Selectively oncolytic mutant of HSV-1 lyses HeLa cells mediated by Ras/RTN3
  • Y. Su, H. Zhu, +12 authors Y. Qi
  • Biology, Chemistry
  • Cancer biology & therapy
  • 1 February 2007
The selectively oncolytic mtHSV, a HSV icp34.5 mutant with lacz gene insertion, was proved that it was targeted for treating tumors but not other organs, however, its oncolytic mechanism is underExpand
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Systemic PCD occurs in TMV-tomato interaction
In hypersensitive response (HR), programmed cell death (PCD) is reported as a powerful defense mechanism in plant immune responses to pathogen. However, little is known about the PCD in systemicExpand
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A Human Lectin Microarray for Sperm Surface Glycosylation Analysis *
Glycosylation is one of the most abundant and functionally important protein post-translational modifications. As such, technology for efficient glycosylation analysis is in high demand. LectinExpand
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Systematic identification of the protein substrates of UDP‐GalNAc:polypeptide N‐acetylgalactosaminyltransferase‐T1/T2/T3 using a human proteome microarray
O‐GalNAc glycosylation is the initial step of the mucin‐type O‐glycosylation. In humans, it is catalyzed by a family of 20 homologous UDP‐GalNAc:polypeptide N‐acetylgalactosaminyltransferasesExpand
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Autophagy contributes to regulate the ROS levels and PCD progress in TMV-infected tomatoes.
Programmed cell death (PCD) and autophagy are both important means for plants to resist pathogen. It is also the main biological reaction of plant immunity. In previous studies, we found that TMVExpand
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Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma
Increasing evidence demonstrates that dysregulation of XBP1 function contributes to tumorigenesis in some cancers. However, little is known about the role of XBP1 in the progression of osteosarcomaExpand
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Nogo-B mediates HeLa cell adhesion and motility through binding of Fibulin-5.
Nogo-B is a known regulator of neural functions and plays an important role in cell adhesion and migration. To our knowledge, the molecular mechanism behind its regulation of cell motility is stillExpand
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Tumor-targeted therapy with a conditionally replicating mutant of HSV-1 induces regression of xenografted human hepatomas
The selectively oncolytic effects of mtHSV, a HSV icp34.5 mutant with lacz gene insertion, on several tumor cells in vitro and its antitumor effects by the intratumoral (IT) route to nude mice loadedExpand
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