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INTRODUCTION Blood pressure is a major cause of cardiovascular disease (CVD) and both may increase as outdoor temperatures fall. However, there are still limited data about seasonal variation in blood pressure and CVD mortality among patients with prior-CVD. METHODS We analysed data on 23 000 individuals with prior-CVD who were recruited from 10 diverse(More)
BACKGROUND Drinking alcohol has a long tradition in Chinese culture. However, data on the prevalence and patterns of alcohol consumption in China, and its main correlates, are limited. METHODS During 2004-08 the China Kadoorie Biobank recruited 512,891 men and women aged 30-79 years from 10 urban and rural areas of China. Detailed information on alcohol(More)
Chronic low-grade inflammation is crucial for the development of insulin resistance and type 2 diabetes mellitus (T2DM), and immunocompetent cells, such as T-cells, B-cells, mast cells and macrophages, regulate the pathogenesis of T2DM. However, little is known about the role of natural killer (NK) and natural killer T (NKT) cells in the pathogenic process(More)
BACKGROUND Despite the great burden of chronic respiratory diseases in China, few large multicentre, spirometry-based studies have examined its prevalence, rate of underdiagnosis regionally or the relevance of socioeconomic and lifestyle factors. METHODS We analysed data from 512 891 adults in the China Kadoorie Biobank, recruited from 10 diverse regions(More)
BACKGROUND Increasing evidence has suggested that major depression (MD) is associated with an increased risk of ischemic heart disease (IHD). We examined this association in Chinese adults using data from the China Kadoorie Biobank study. METHODS AND RESULTS Over 0.5 million adults aged 30 to 79 years were followed from baseline interview (2004-2008)(More)
Objective: To investigate the expression change and their clinical significance of serum CEA, CYFRA21-1 and ProGRP before and after IP regimen in the treatment of non small cell lung cancer. Methods: 48 cases with NSCLC were selected as the observation group and 34 healthy people were selected as the control group. The serum levels of CEA, CYFRA21-1 and(More)
Lung ischemia/reperfusion injury (LIRI) usually occurs during in lung transplantation and extracorporeal circulation operation and may develop into pulmonary infections, acute rejection and bronchiolitis obliterans syndrome. Recent studies have discovered the protective effect of heat shock protein 70 (HSP70) on various types of injuries. In the present(More)
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