Shukrallah Zaynoun

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Nine patients with extensive pityriasis alba were studied using histopathological and histochemical techniques and electron microscopy. There was a reduction in the density of functional melanocytes in the affected areas without any change in their cytoplasmic activity. The melanosomes tended to be fewer and smaller, but their distribution pattern in the(More)
For fair Caucasian skin, the minimal delayed erythema dose (MED) 24 hr after exposure to broadband UVA is about 1200 times greater than the MED of broadband UVB, for both single and multiple daily exposures. Repeated daily exposure to doses less than MED results in cumulative effects manifest by gradual lowering of the daily dose threshold for delayed(More)
Superantigens are powerful T lymphocyte-stimulating agents that are believed to contribute to the pathogenesis of certain diseases such as psoriasis. Toxins produced by Streptococcus pyogenes and Staphylococcus aureus are superantigens. The aim of this study was to detect genes that code for superantigens in Streptococcus and Staphylococcus aureus isolates(More)
The clinical and histopathologic features of actinic lichen planus in 16 patients were studied. The majority of the patients were young, and men and women were almost equally affected. The relative incidence of this condition, compared with the incidence of all forms of lichen planus, was smaller than that reported in the literature. The eruption was(More)
The significance of sun exposure in the pathogenesis of basal cell carcinoma (BCC) was assessed. A total of 262 tumors were studied. Most of the tumors occurred in patients over 40 years of age, with a male to female ratio of 3:2. The majority of tumors were present on the head and neck, mostly on sites maximally exposed to sun. Solar elastosis of varying(More)
Fifty-seven patients with primary localized cutaneous amyloidosis (PLCA) were clinically and histopathologically reviewed. Two-thirds of patients had macular amyloidosis (MA). Intermediate cases having macular lesions with micropapules and/or lichens were identified. A spectrum for the disease is proposed, in which the less itchy classical macular variant(More)
Despite the decline in the incidence of berloque dermatitis during the past decade, milder cases resulting from the presence of relatively small quantities of bergapten in perfumed cosmetics continue to occur. The resultant hyperpigmentation may have an atypical presentation leading to error in diagnosis. In addition, the condition can sometimes induce or(More)
Ultrastructural studies were carried out on the invasive nodule of forty malignant melanomas. The findings support the concept that the fine structure of lentigo maligna melanoma is often characteristic, and differs from that of superficial spreading and nodular melanoma. The melanosomes in lentigo maligna melanoma are usually ellipsoidal and resemble those(More)