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STUDY DESIGN An in vitro biomechanical investigation to quantify the endplates resistance to compressive loads, in the thoracic and lumbar spine. Comparisons were made to determine the regional strength of the endplate, the optimal size and geometry of interbody support, and the effects of endplate removal on structural strength. OBJECTIVES To(More)
STUDY DESIGN Anterior single- and dual-rod instrumented human and ovine thoracolumbar spines, with and without structural interbody support (SIS), were biomechanically tested and compared in flexion, lateral bending, and torsion. OBJECTIVE To determine significant differences in global stiffness of the constructs in an attempt to clarify specific(More)
Essential oils from common spices such as nutmeg, ginger, cardamom, celery, xanthoxylum, black pepper, cumin, and coriander were tested for their ability to suppress the formation of DNA adducts by aflatoxin B1 in vitro in a microsomal enzyme-mediated reaction. All oils were found to inhibit adduct formation very significantly and in a dose-dependent(More)
The present study deals with the chemopreventive action of the food-seasoning spices mixture Garam masala on dimethylbenz[a]anthracene (DMBA)-induced translactational and transplacental carcinogenesis in mice. When pregnant mice were given 10 and 30 mg of Garam masala per day from Days 13-19 of gestation in addition to DMBA (5 mg/day) on Days 15-17 of(More)
The present study examines the transmammary modulation of the glutathione system of enzymes in the F1 generation of mouse pups postnatally exposed to malathion. Lactating Swiss albino mice received either 30 or 100 mg malathion kg-1 body wt. (98% pure) for 14 or 21 days postpartum. The acid-soluble sulphydryl content was significantly increased (P < 0.001)(More)
The present study reports the chemopreventive potential of the oil from mustard seed on 7,12-dimethylbenz[a]anthracene-induced transplacental and translactational carcinogenesis in Swiss albino mice. Gestating females were treated with mustard oil at dose levels of 0.05 and 0.10 ml per day from days 13 to 19 of gestation. In addition, they were given DMBA(More)
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